Results 151 to 160 of about 35,325 (217)
Curcumin improves bladder dysfunction in diabetic rats by attenuating oxidative stress via the Keap1/NRF2/HO-1 pathway. [PDF]
Zheng JH +5 more
europepmc +1 more source
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao +6 more
wiley +1 more source
<i>STK11</i> as an Emerging Biomarker in Non-Small Cell Lung Cancer. [PDF]
Kulkarni AA +6 more
europepmc +1 more source
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal +4 more
wiley +1 more source
Polyphyllin B induces ferroptosis in triple-negative breast cancer by inactivating NRF2. [PDF]
Deng P +7 more
europepmc +1 more source
Urolithin A (UA) treatment enhances the Nrf2/HO‐1‐mediated antioxidant capacity against ischemic injury postischemic stroke, while also effectively suppressing neuroinflammatory responses. Both of these regulatory effects are likely associated with the NF‐κB signaling pathway, which in turn inhibits neuronal apoptosis and contributes to the improvement
Yanxin Shao +9 more
wiley +1 more source
Unveiling novel antioxidant peptides from silver carp (<i>Hypophthalmichthys molitrix</i>) bone collagen and underlying multi-dimensional mechanism by integrating <i>in silico</i>, <i>in vitro</i>, and <i>in cellulo</i> approaches. [PDF]
Mei Y +9 more
europepmc +1 more source
Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu +4 more
wiley +1 more source

