Results 1 to 10 of about 29,071 (276)
Superior Antiproliferative and Enhanced Synergistic Effects of a ROCK Inhibitor in Multiple Models for Keloid Disease [PDF]
JID InnovationsKeloid disease is a common fibroproliferative skin disorder characterized by excessive scar tissue formation and frequent recurrence. Limited therapies and study models hinder progress in addressing this unmet clinical need.
Zeinab Ghasemishahrestani +3 more
doaj +2 more sources
The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models
Frontiers in Cell and Developmental Biology, 2020 Keloids constitute an abnormal fibroproliferative wound healing response in which raised scar tissue grows excessively and invasively beyond the original wound borders.
Grace C Limandjaja, Sue Gibbs
exaly +3 more sources
Ubiquitin-related Protein IFNGR1 as Causal Factor and Drug Target for Keloids: A Mendelian Randomization Analysis [PDF]
Plastic and Reconstructive Surgery, Global OpenBackground:. Keloids, benign skin tumors due to connective tissue overgrowth, can be exacerbated by ubiquitin-proteasome system abnormalities through uncontrolled inflammation.
Yeltai Nurzat, PhD +7 more
doaj +2 more sources
Marked regression of a chronic elbow keloid after a single intralesional corticosteroid injection: a case report [PDF]
Journal of Medical Case ReportsBackground Keloid scars can be challenging to manage, especially in resource-limited settings. This case demonstrates successful regression of a chronic keloid with a single intralesional corticosteroid injection.
Peyman Khaledi
doaj +2 more sources
Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures [PDF]
, 2001 BACKGROUND: The treatment of keloids and hypertrophic scars has been difficult and a recent French study showed that bleomycin has been useful in the treatment of these lesions.
España, A. (Agustín) +2 more
core +3 more sources
6: Biomimetic Microtissue Keloid Scar System Using Keloid-derived Fibroblasts and Macrophages
Plastic and Reconstructive Surgery, Global Open, 2021 Purpose: Keloid is a disease that affects millions of patients and has relatively few effective treatment options. Unfortunately, traditional 2D monolayer culture of keloid derived fibroblasts show little resemblance to the pathological process in vivo ...
Yu Tan, Ph.D +4 more
doaj +1 more source
The epigenetics of keloids [PDF]
Experimental Dermatology, 2021 AbstractKeloid scarring is a fibroproliferative disorder of the skin with unknown pathophysiology, characterised by fibrotic tissue that extends beyond the boundaries of the original wound. Therapeutic options are few and commonly ineffective, with keloids very commonly recurring even after surgery and adjunct treatments.
Mark W. Fear +6 more
openaire +3 more sources
Biomaterials Research, 2022 Silicone breast implants are commonly used for cosmetic and oncologic surgical indications owing to their inertness and being nontoxic. However, complications including capsular contracture and anaplastic large cell lymphoma have been associated with ...
Fatemeh Tavakoli Foroushani +5 more
doaj +1 more source