Is leukotriene B4 one of the keloid marker? a fibroblast keloid study
Dermatology Reports, 2019 Keloid pathogenesis occurs due to the duration of prolonged inflammatory phase and increased production of various growth factors such as TGF-β1 which may cause increasing fibroblast proliferation and collagen synthesis.
Yuli Kurniawati +3 more
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An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease [PDF]
, 2015 Background: Glucocorticoids (GCs) are first-line treatment for keloid disease (KD) but are limited by high incidence of resistance, recurrence and undesirable sideeffects. Identifying patient responsiveness early could guide therapy.
Bayat, A +6 more
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Pan African Medical Journal, 2018 A 24-year-old man underwent left ear tympanoplasty for chronic otitis media and 3 months later started developing asymptomatic, tumor-like, cutaneous lesion over the incision site. There was no pain or itching. The lesion gradually progressed in the subsequent years protruding behind the ear to cause apparent cosmetic deformity. A clinical diagnosis of
Pirabu Sakthivel, Chirom Amit Singh
openaire +3 more sources
Frontiers in Physiology, 2017 Several studies have reported on certain aspects of the characteristics of different sites within a keloid lesion, but detailed studies on the keloid dermis at different depths within a keloid lesion are scarce.
Hu Jiao +3 more
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Sister Mary Joseph's Nodule at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 34 cases. [PDF]
, 2013 Sister Mary Joseph's nodule is a metastatic tumor deposit in the umbilicus and often represents advanced intra-abdominal malignancy with dismal prognosis. There is a paucity of published data on this subject in our setting.
A Dubreuil +35 more
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Keloids and Hypertrophic Scars: Update and Future Directions [PDF]
, 2014 Summary: The development of cutaneous pathological scars, namely, hypertrophic scars (HSs) and keloids, involves complex pathways, and the exact mechanisms by which they are initiated, evolved, and regulated remain to be fully elucidated.
Akaishi, Satoshi +3 more
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Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration. [PDF]
, 2015 BackgroundSkin fibrosis is a significant medical problem that leads to a functional, aesthetic, and psychosocial impact on quality-of-life. Light-emitting diode-generated 633-nm red light (LED-RL) is part of the visible light spectrum that is not known ...
Isseroff, R Rivkah +4 more
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Control of the skin scarring response [PDF]
, 2009 There comes a time when the understanding of the cutaneous healing process becomes essential due to the need for a precocious tissue repair to reduce the physical, social, and psychological morbidity.
Ferreira, Lydia Masako +3 more
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Defining a Unique Gene Expression Profile in Mature and Developing Keloids
JID Innovations, 2023 Keloids are benign, fibroproliferative dermal tumors that typically form owing to abnormal wound healing. The current standard of care is generally ineffective and does not prevent recurrence.
Yuan O. Zhu +13 more
doaj +1 more source
IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation
JCI Insight, 2023 Keloids are considered the manifestation of a fibroproliferative disease characterized by chronic inflammation that is induced following skin injury. Deciphering the underlying mechanism of keloid formation is essential for improving treatment outcomes ...
Hua Chao +10 more
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