Results 31 to 40 of about 40,839 (332)

The Roles of Inflammation in Keloid and Hypertrophic Scars

Frontiers in Immunology, 2020
The underlying mechanisms of wound healing are complex but inflammation is one of the determining factors. Besides its traditional role in combating against infection upon injury, the characteristics and magnitude of inflammation have dramatic impacts on
Zheng-Cai Wang, Wan-Yi Zhao, Yangyang Cao, Yan-Qi Liu, Qihang Sun, P. Shi, Jiaxing Cai, Xiao Z. Shen, Wei-Qiang Tan   +8 more
semanticscholar   +1 more source

Silencing circular RNAPTPN12 promoted the growth of keloid fibroblasts by activating Wnt signaling pathway via targeting microRNA-21-5p

Bioengineered, 2022
Keloid is a skin disease marked by fibroplasia, and fibroblasts viability plays a considerable part in keloid. Our research was devoted to assessing the involvement and mechanism of circPTPN12 in keloid.
Fei Liu, Tao Li, Xiao-Juan Zhan
semanticscholar   +1 more source

Expression of fibroblast-activation protein in keloid tissue and its clinical significance

Pifu-xingbing zhenliaoxue zazhi, 2020
Objective: To investigate the expression of fibroblast-activation protein(FAP) in keloid tissue and its role in the development of keloid. Methods: Immunochemical staining was used to evaluate the expression of FAP in 30 cases of keloid tissue (case ...
Yu-xiong ZOU, Ming-chun CHEN, Li-da XU
doaj   +1 more source

Axillary Keloid Formation after Osmidrosis Surgery [PDF]

Archives of Aesthetic Plastic Surgery, 2013
Keloid is a scar tissue that undergoes recovery and excessive growth over the original wounds when the collagen is excessively accumulated in the dermis during the wound healing process.
So-Min Hwang, Sang-Hwan Lee, Hyung-Do Kim, Yong-Hui Jung, Hong-il Kim   +4 more
doaj   +1 more source

Turner syndrome and associated problems in turkish children: A multicenter study [PDF]

, 2015
Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls.
Abacı, A., Abalı, S., Adal, E., Akın, L., Akıncı, A., Akyürek, N., Andıran, N., Anık, A., Atabek, M.E., Ataş, A., Aydın, B.K., Açıkel, C., Baş, F., Baş, S., Baş, V.N., Bereket, A., Binay, Ç., Bolu, S., Bondy, C., Bulan, K., Büyükinan, M., Can, H.D., Cinaz, P., Darcan, Ş., Darendeliler, F., Demir, K., Demirbilek, H., Demirel, F., Doğan, D., Doğan, M., Döneray, H., Dündar, B., Eklioğlu, B.S., Emeksiz, H.C., Ercan, O., Eren, E., Ersoy, B., Evliyaoğlu, O., Fidancı, K., Gökşen, D., Gül, D., Gürbüz, F., Hatun, Ş., Kaba, S., Kara, C., Karagüzel, G., Keskin, M., Kızılay, D., Orbak, Z., Pirgon, Ö., Polat, A., Poyrazoğlu, Ş., Sarı, E., Sağlam, H., Tarım, Ö., Tepe, D., Topaloğlu, A.K., Turan, S., Yeşilkaya, E., Yüksel, B., Çakır, E.D., Çatlı, G., Çelik, N., Çizmecioğlu, F., Ökten, A., Önal, H., Özbek, M.N., Özen, S., Özgen, T., Özhan, Bayram, Özkan, B., Ünüvar, T., Şen, Y., Şimşek, E.   +73 more
core   +1 more source

Botulinum Toxin A for the Treatment of Keloids [PDF]

, 2012
Introduction: Keloids are the result of excessive scar tissue formation. Besides their poor aesthetic appearance, keloids can be associated with severe clinical symptoms such as pain, itching, and rigidity.
Bureik, D., Dombrowski, Yvonne, Gauglitz, Gerd, Pavicic, T., Ruzicka, Thomas, Schauber, Jürgen   +5 more
core   +1 more source

Secreted Factors from Keloid Keratinocytes Modulate Collagen Deposition by Fibroblasts from Normal and Fibrotic Tissue: A Pilot Study

Biomedicines, 2020
Interactions between keratinocytes and fibroblasts in the skin layers are crucial in normal tissue development, wound healing, and scarring. This study has investigated the role of keloid keratinocytes in regulating collagen production by primary ...
Mansour A. Alghamdi, Laith N. AL-Eitan, Andrew Stevenson, Nutan Chaudhari, Nicole Hortin, Hilary J. Wallace, Patricia L. Danielsen, Mitali Manzur, Fiona M. Wood, Mark W. Fear   +9 more
doaj   +1 more source

Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid [PDF]

, 2009
Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix in the dermis. The keloid matrix contains excess collagen and glycosaminoglycans (GAGs), but lacks elastic fiber. However, the roles of these matrix components in
Ikeda, Mika, Ishiko, Toshihiro, Kubota, Hiroshi, Kurokawa, Masako, Nagata, Kazuhiro, Naitoh, Motoko, Nakamura, Tomiyuki, Suzuki, Shigehiko, Utani, Atsushi, Yamawaki, Satoko, Yoshikawa, Katsuhiro   +10 more
core   +1 more source

Current Advances in Hypertrophic Scar and Keloid Management

Seminars in Plastic Surgery, 2021
Hypertrophic scars and keloids are caused by excessive tissue response to dermal injury due to local fibroblast proliferation and collagen overproduction.
N. Barone, Tyler Safran, J. Vorstenbosch, Peter G. Davison, S. Cugno, A. Murphy   +5 more
semanticscholar   +1 more source

MicroRNA-21 may be involved in the therapeutic effects of Galla chinensis ointment on keloid

Journal of International Medical Research, 2020
Objective Galla chinensis ointment can inhibit the proliferation of keloid fibroblasts and decrease keloid formation. We investigated whether Galla chinensis ointment inhibits keloid fibroblast proliferation through expression of microRNA-21 ...
Zhiming Tang, Jicun Ding, Xiaoxiang Zhai, Mengqing Jing, Zhiqiang Guan, Yongcong Li   +5 more
doaj   +1 more source