Results 41 to 50 of about 29,071 (276)

Mutations in MAP3K7 that Alter the Activity of the TAK1 Signaling Complex Cause Frontometaphyseal Dysplasia. [PDF]

open access: yes, 2016
Frontometaphyseal dysplasia (FMD) is a progressive sclerosing skeletal dysplasia affecting the long bones and skull. The cause of FMD in some individuals is gain-of-function mutations in FLNA, although how these mutations result in a hyperostotic ...
Addor, M.C.   +29 more
core   +3 more sources

KELOID; PRODUCTION OF KELOID ANIMAL MODEL

open access: yesTHE PROFESSIONAL MEDICAL JOURNAL, 2016
Keloids and hypertrophic scars are basically an overabundance of fibrosis in cutaneous healing process. Unfortunately, keloids are only found in human beings. So far no successful animal model of keloid has been reported. Objectives: To produce an animal model of keloid. Main Outcome Measure: Animal model of keloid.
Abdul Mannan Babar, A. H. Nagi
openaire   +2 more sources

Single-cell RNA-seq reveals the communications between extracellular matrix-related components and Schwann cells contributing to the earlobe keloid formation

open access: yesFrontiers in Medicine, 2022
Keloid is a major type of skin fibrotic disease, with one prominent feature of extensive accumulation of extracellular matrix (ECM) components, and another feature of pain/itching, which is closely related to the peripheral nervous system (PNS). However,
Taogen Gong   +8 more
doaj   +1 more source

Different therapeutic modalities in a patient with multiple spontaneously developed keloids: a case report [PDF]

open access: yes, 2006
Keloids are benign tumors that usually develop as an excessive healing response to injury. They remain a challenging therapeutic problem to this day. Numerous treatment approaches are available, yet therapeutic results are often not satisfactory.
Bukvić-Mokos, Zrinka   +2 more
core  

Comparative dermatology [PDF]

open access: yes, 2006
The authors show a case of keloid that is reminiscent of the bow-tie, a male piece of apparel.Os autores relatam um caso de quelóide que reporta à gravata borboleta, acessório de trajes em geral masculinos.Universidade Federal de Juiz de Fora Hospital ...
Fraga, Juliana Cristina Silva   +2 more
core   +5 more sources

Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco   +4 more
wiley   +1 more source

Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis [PDF]

open access: yesPeerJ
Background Keloid is a chronic proliferative fibrotic disease caused by abnormal fibroblasts proliferation and excessive extracellular matrix (ECM) production.
Liu Yang, Xiuli Li, Yanli Wang
doaj   +2 more sources

Translational Extracellular Matrix Spray‐Coating Approach for Large‐Scale Bioactive Surface Functionalization and Tissue Repair

open access: yesAdvanced Healthcare Materials, EarlyView.
A translational spray‐coating strategy that conformationally activates fibronectin and collagen via mechanical unfolding is presented. Microscale droplets enable uniform extracellular matrix (ECM) depositions on biomedical substrates and wound closure enhancement.
Albertus Ivan Brilian   +11 more
wiley   +1 more source

A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated Signaling

open access: yesActa Dermato-Venereologica, 2017
Keloid disease is a fibroproliferative tumour characterised by aggressive local invasion, evident from a clinically and histologically active migrating margin.
Natalie Jumper   +3 more
doaj   +1 more source

Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden

open access: yesActa Dermato-Venereologica, 2023
Keloids are skin tumours caused by aberrant growth of dermal fibroblasts. Cellular senescence contributes to aging and various pathological conditions, including cancer, atherosclerosis, and fibrotic diseases.
Claudia C. Darmawan   +5 more
doaj   +1 more source

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