Results 41 to 50 of about 29,071 (276)
Mutations in MAP3K7 that Alter the Activity of the TAK1 Signaling Complex Cause Frontometaphyseal Dysplasia. [PDF]
Frontometaphyseal dysplasia (FMD) is a progressive sclerosing skeletal dysplasia affecting the long bones and skull. The cause of FMD in some individuals is gain-of-function mutations in FLNA, although how these mutations result in a hyperostotic ...
Addor, M.C. +29 more
core +3 more sources
KELOID; PRODUCTION OF KELOID ANIMAL MODEL
Keloids and hypertrophic scars are basically an overabundance of fibrosis in cutaneous healing process. Unfortunately, keloids are only found in human beings. So far no successful animal model of keloid has been reported. Objectives: To produce an animal model of keloid. Main Outcome Measure: Animal model of keloid.
Abdul Mannan Babar, A. H. Nagi
openaire +2 more sources
Keloid is a major type of skin fibrotic disease, with one prominent feature of extensive accumulation of extracellular matrix (ECM) components, and another feature of pain/itching, which is closely related to the peripheral nervous system (PNS). However,
Taogen Gong +8 more
doaj +1 more source
Different therapeutic modalities in a patient with multiple spontaneously developed keloids: a case report [PDF]
Keloids are benign tumors that usually develop as an excessive healing response to injury. They remain a challenging therapeutic problem to this day. Numerous treatment approaches are available, yet therapeutic results are often not satisfactory.
Bukvić-Mokos, Zrinka +2 more
core
The authors show a case of keloid that is reminiscent of the bow-tie, a male piece of apparel.Os autores relatam um caso de quelóide que reporta à gravata borboleta, acessório de trajes em geral masculinos.Universidade Federal de Juiz de Fora Hospital ...
Fraga, Juliana Cristina Silva +2 more
core +5 more sources
Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco +4 more
wiley +1 more source
Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis [PDF]
Background Keloid is a chronic proliferative fibrotic disease caused by abnormal fibroblasts proliferation and excessive extracellular matrix (ECM) production.
Liu Yang, Xiuli Li, Yanli Wang
doaj +2 more sources
A translational spray‐coating strategy that conformationally activates fibronectin and collagen via mechanical unfolding is presented. Microscale droplets enable uniform extracellular matrix (ECM) depositions on biomedical substrates and wound closure enhancement.
Albertus Ivan Brilian +11 more
wiley +1 more source
A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated Signaling
Keloid disease is a fibroproliferative tumour characterised by aggressive local invasion, evident from a clinically and histologically active migrating margin.
Natalie Jumper +3 more
doaj +1 more source
Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden
Keloids are skin tumours caused by aberrant growth of dermal fibroblasts. Cellular senescence contributes to aging and various pathological conditions, including cancer, atherosclerosis, and fibrotic diseases.
Claudia C. Darmawan +5 more
doaj +1 more source

