Expression of transforming growth factor-beta isoforms and their receptors in chronic tendinosis [PDF]
, 2001 Chronic tendon lesions are degenerative conditions and may represent a failure to repair or remodel the extracellular matrix after repeated micro-injury.
Curry, V +5 more
core +2 more sources
The Efficacy of Triamcinolone Acetonide in Keloid Treatment: A Systematic Review and Meta-analysis [PDF]
, 2016 published_or_final_versio
Chan, YW +4 more
core +1 more source
Schwann cells contribute to keloid formation
medRxiv, 2021 Keloids are disfiguring, hypertrophic scars with yet poorly understood pathomechanisms, which could lead to severe functional impairments. Here we analyzed the characteristics of keloidal cells by single cell sequencing and discovered the presence of an ...
M. Direder +17 more
semanticscholar +1 more source
Differential expression of cyclooxygenases in hypertrophic scar and keloid tissues [PDF]
, 2009 Hypertrophic scar (HS) and keloid (KL) are two forms of an abnormal cutaneous scarring process, mainly characterized by excessive extracellular matrix deposition and fibroblast proliferation.
ABBONDANZA C. +8 more
core +1 more source
Is leukotriene B4 one of the keloid marker? a fibroblast keloid study
Dermatology Reports, 2019 Keloid pathogenesis occurs due to the duration of prolonged inflammatory phase and increased production of various growth factors such as TGF-β1 which may cause increasing fibroblast proliferation and collagen synthesis.
Yuli Kurniawati +3 more
doaj +1 more source
Frontiers in Physiology, 2017 Several studies have reported on certain aspects of the characteristics of different sites within a keloid lesion, but detailed studies on the keloid dermis at different depths within a keloid lesion are scarce.
Hu Jiao +3 more
doaj +1 more source
An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease [PDF]
, 2015 Background: Glucocorticoids (GCs) are first-line treatment for keloid disease (KD) but are limited by high incidence of resistance, recurrence and undesirable sideeffects. Identifying patient responsiveness early could guide therapy.
Bayat, A +6 more
core +1 more source
Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases
Experimental Dermatology, 2020 Keloid disorder, a group of fibroproliferative skin diseases, is characterized by unremitting accumulation of the extracellular matrix (ECM) of connective tissue, primarily collagen, to develop cutaneous tumors on the predilection sites of skin. There is
E. Macarak +3 more
semanticscholar +1 more source
Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration. [PDF]
, 2015 BackgroundSkin fibrosis is a significant medical problem that leads to a functional, aesthetic, and psychosocial impact on quality-of-life. Light-emitting diode-generated 633-nm red light (LED-RL) is part of the visible light spectrum that is not known ...
Isseroff, R Rivkah +4 more
core +3 more sources
KELOID; PRODUCTION OF KELOID ANIMAL MODEL
THE PROFESSIONAL MEDICAL JOURNAL, 2016 Keloids and hypertrophic scars are basically an overabundance of fibrosis in cutaneous healing process. Unfortunately, keloids are only found in human beings. So far no successful animal model of keloid has been reported. Objectives: To produce an animal model of keloid. Main Outcome Measure: Animal model of keloid.
Abdul Mannan Babar, Abdul Hannan Nagi
openaire +2 more sources