Results 131 to 140 of about 6,637 (212)

Localization and expression of CHST6 and keratan sulfate proteoglycans in the human cornea.

, 2010
Macular corneal dystrophy (MCD; OMIM 217800) is a rare autosomal recessive inherited disorder causedby mutations in the carbohydrate sulfotransferase 6 (CHST6) and characterised by the presence ofunsulfated keratan sulfate proteoglycans (KSPGs) forming ...
Bertolin M, Barbaro V, Fasolo A, VOLPI, Nicola, Arnaldi R, Prosdocimo G, Volpi N, Ferrari B, Brusini P, Ponzin D, Di Iorio E, DI IORIO, MARIO VINCENZO, Ferrari S.   +12 more
core   +1 more source

An improved method for the structural profiling of keratan sulphates : analysis of keratan suplhates from brain and ovarian tumours.

, 1999
A previously developed method for the structural fingerprinting of keratan sulfates (Brown et al., Glycobiology, 5, 311-317, 1995) has been adapted for use with oligosaccharides fluorescently labeled with 2- aminobenzoic acid following keratanase II ...
Nieduszynski, Ian A., Andrew, S. M., Brown, Gavin M., Hadley, J. L., Morris, H. G., Whitham, K. M.   +5 more
core  

600 MHz NMR studies of human articular cartilage keratan sulfates.

, 1999
The use of high-field two-dimensional 1H-correlation data is described for the detailed comparison of intact keratan sulfate polymer chains derived from human articular cartilage sources as a function of age.
Huckerby, Thomas N., Bayliss, Michael T., Nieduszynski, Ian A., Brown, Gavin M.   +3 more
core  

Synthesis of and characterization of differentially sulfated disaccharide repeating units of keratan sulfate. [PDF]

Glycosci Ther
Das A, Kashiwagi GA, Gan Q, Shadrick ML, Montaño AM, Demchenko AV.   +5 more
europepmc   +1 more source

Increased expression of highly sulfated keratan sulfate synthesized in malignant astrocytic tumors. Biochem Biophys Res Commun 369:1041–1046

, 2008
Keratan sulfate (KS) proteoglycan is expressed in the extracellular matrix or cell surface in numerous tissues, predominantly in those of the cornea, cartilage, and brain. However, its structure, function, and regulation remain poorly understood.
Mika Kato Kaneko, Hisashi Narimatsu, Yukinari Kato, Satoshi Ogasawara, Norihito Hayatsu   +4 more
core  

Enzymatic basis of branching and extension of O-Man glycans for keratan sulfate biosynthesis. [PDF]

J Biol Chem
Itoh T, Tanaka HN, Pareek M, Nagae M, Manya H, Ido A, Mishra SK, Kizuka Y.   +7 more
europepmc   +1 more source

Human aggrecan keratan sulfate undergoes structural changes during adolescent development

, 1998
Alkaline borohydride-reduced keratan sulfate chains were isolated from human articular cartilage aggrecan from individuals of various ages (0-85 years old).
Nieduszynski, I A, Brown, Gavin, Huckerby, T N, Bayliss, M T   +3 more
core  

Keratan Sulfate Is a Multifunctional Brain Glycosaminoglycan With Instructive Capabilities. [PDF]

J Neurochem
Melrose J.
europepmc   +1 more source

Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides. [PDF]

Sci Rep, 2020
Miller MC, Cai C, Wichapong K, Bhaduri S, Pohl NLB, Linhardt RJ, Gabius HJ, Mayo KH.   +7 more
europepmc   +1 more source

Expression of Heart Development Protein With EGF-Like Domains 1 (HEG1) Decorated With Low-Sulfated Keratan Sulfate in Human Malignant Pleural Mesothelioma. [PDF]

Pathol Int
Nakashima K, Hoshino H, Zhang Z, Akama TO, Kondo N, Hasegawa S, Sekido Y, Fukushima M, Ishizuka T, Kobayashi M.   +9 more
europepmc   +1 more source