Results 131 to 140 of about 5,745 (171)
Some of the next articles are maybe not open access.
Detection of keratan sulfate by immunological methods in commercial chondroitin sulfate preparations
Carbohydrate Polymers, 2014Chondroitin sulfate (CS), a well known nutraceutical, and keratan sulfate (KS) are glycosaminoglycans involved in the structure of cartilage proteoglycan, aggrecan. Since CS is extracted from cartilage, there may be a possibility that purified CS is contaminated with small amount of KS.
Lech Ozimek, Takuo Nakano
exaly +3 more sources
Immunoblotting Assays for Keratan Sulfate
Analytical Biochemistry, 2002The detection of microquantities of glycosaminoglycans (GAGs) in biological samples has been hampered by the lack of sensitive methods. In this paper we describe the modification and development of three sensitive assays capable of detecting nanogram quantities of GAGs in biological samples. The first assay detects total GAGs.
Jung Hae, Yoon +2 more
openaire +2 more sources
The Linkage of Corneal Keratan Sulfate to Protein
Connective Tissue Research, 1975The linkage of corneal keratan sulfate to protein has been investigated. After exhaustive digestion of bovine corneas with papain and pronase, a product was obtained in which aspartic acid was the predominant amino acid and constituted 59% of the total amino acids.
J R, Baker, J A, Cifonelli, L, Rodén
openaire +2 more sources
Water vapor sorption of keratan sulfate
Molecular and Cellular Biochemistry, 1975Keratan sulfate was isolated from bovine cornea. The water vapor sorption isotherms were obtained on both sodium and calcium salts of keratan sulfate at different temperatures. Deuterated water sorption isotherms were obtained on sodium keratan sulfates.
B, Plessy, F A, Bettelheim
openaire +2 more sources
Vacuum ultraviolet circular dichroism of keratan sulfate
Biochimica et Biophysica Acta (BBA) - General Subjects, 1987The vacuum ultraviolet CD of keratan sulfate reveals an intense negative CD band at 171 nm. Its intensity can be rationalized with a recently proposed quadrant rule in terms of the acetamido group being slightly tilted toward the hexosaminidic linkage oxygen.
E S, Stevens, B, Lin
openaire +2 more sources
Keratan sulfate in body fluids in joint disease
Acta Orthopaedica Scandinavica, 1995Keratan sulfate (KS) is a highly-negatively charged glycosaminoglycan which is found principally in aggrecan, the most abundant proteoglycan in the extracellular matrix of hyaline, fibrous and elastic cartilage. In 1985, we discovered that small peptidoglycans bearing antigenic KS (agKS) were present in small amounts in human serum and postulated that ...
Thonar, Eugene J-M A +5 more
openaire +3 more sources
Biosynthesis of Keratan Sulfate
2009Keratan sulfate (KS) is a poly-sulfated glycosaminoglycan with a poly-N-acetyllactosamine linear chain structure. KS is a rich component in cornea, and is also present in cartilage and brain. In cornea, KS plays important roles in maintaining water content and developing collagen matrix. Recent studies have demonstrated its association with Alzheimer’s
Akira Seko, Katsuko Yamashita
openaire +1 more source
Identification and quantitation of keratan sulfate in urine
Clinica Chimica Acta, 1974Abstract The purpose of the present artical is to indicate reliable and specific methods for identification and quantitation of keratan sulfate in urine. Thinlayer chromatography on silica gel or cellulose allows rapid and specific characterization, whereas prior isolation on Dowex 1×2 with selective elution with 3.0 M NaCl only allows quantitative ...
openaire +2 more sources
Keratan sulfate exacerbates experimental autoimmune encephalomyelitis
Journal of Neuroscience Research, 2015Proteoglycans (PGs) are the components of extracellular matrices in the central nervous system (CNS). Keratan sulfate (KS) is a glycosaminoglycan that is included in the KSPG that acts as an inhibitory factor in nerve regeneration after CNS injury. To investigate the role of KS in immune diseases, we induced experimental autoimmune encephalomyelitis ...
Rino, Ueno +5 more
openaire +2 more sources
Mannose in the Keratan Sulfate from Bovine Cornea
The Journal of Biochemistry, 1982After exhaustive digestion of bovine corneas with a protease, keratan sulfate fractions of different chain length were obtained by ethanol fractionation on a cellulose column, followed by ion-exchange column chromatography. Compositional analysis of these fractions showed that aspartic acid is the predominant amino acid and that the keratan sulfate in ...
H, Yamaguchi, T, Nakai
openaire +2 more sources