Results 221 to 230 of about 410,791 (266)
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Keratan sulfate: an up-to-date review.
International Journal of Biological Macromolecules, 2015Keratan sulfate (KS) is a glycosaminoglycan (GAG) type consisted of a sulfated poly-N-acetyl lactosamine chain. Besides acting as a constitutive molecule of the extracellular matrices, this GAG also plays a role as a hydrating and signaling agent in cornea and cartilage tissues. Inasmuch, KS is widely explored in the pharmaceutical industry.
V. Pomin
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Keratan sulfate: biosynthesis, structures, and biological functions.
Methods in molecular biology, 2015Keratan sulfate is a glycosaminoglycan that has been investigated in the cornea and skeletal tissues for decades. Endoglycosidases and monoclonal antibodies specific for keratan sulfate have been developed. These materials have facilitated the analysis of keratan sulfate biosynthesis and structures. Likewise, they have expedited study of the biological
K. Uchimura
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Imaging Keratan Sulfate in Ocular Tissue Sections by Immunofluorescence Microscopy and LA-ICP-MS.
ACS Applied Bio Materials, 2022Carbohydrate-specific antibodies can serve as valuable tools to monitor alterations in the extracellular matrix resulting from pathologies. Here, the keratan sulfate-specific monoclonal antibody MZ15 was characterized in more detail by immunofluorescence
Burak Boyraz +9 more
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Detection of keratan sulfate by immunological methods in commercial chondroitin sulfate preparations
Carbohydrate Polymers, 2014T. Nakano, L. Ozimek
exaly +2 more sources
Electrophoresis, 2020
Chondroitin sulfate is extracted from animal cartilaginous tissues and is commercialized as active principle against osteoarthritis. Its biological activity depends on its purity grade and could be altered by the presence of other glycosaminoglycans like
O. F. Restaino, M. de Rosa, C. Schiraldi
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Chondroitin sulfate is extracted from animal cartilaginous tissues and is commercialized as active principle against osteoarthritis. Its biological activity depends on its purity grade and could be altered by the presence of other glycosaminoglycans like
O. F. Restaino, M. de Rosa, C. Schiraldi
semanticscholar +1 more source
Immunoblotting Assays for Keratan Sulfate
Analytical Biochemistry, 2002The detection of microquantities of glycosaminoglycans (GAGs) in biological samples has been hampered by the lack of sensitive methods. In this paper we describe the modification and development of three sensitive assays capable of detecting nanogram quantities of GAGs in biological samples. The first assay detects total GAGs.
Jung Hae, Yoon +2 more
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Water vapor sorption of keratan sulfate
Molecular and Cellular Biochemistry, 1975Keratan sulfate was isolated from bovine cornea. The water vapor sorption isotherms were obtained on both sodium and calcium salts of keratan sulfate at different temperatures. Deuterated water sorption isotherms were obtained on sodium keratan sulfates.
B, Plessy, F A, Bettelheim
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Vacuum ultraviolet circular dichroism of keratan sulfate
Biochimica et Biophysica Acta (BBA) - General Subjects, 1987The vacuum ultraviolet CD of keratan sulfate reveals an intense negative CD band at 171 nm. Its intensity can be rationalized with a recently proposed quadrant rule in terms of the acetamido group being slightly tilted toward the hexosaminidic linkage oxygen.
E S, Stevens, B, Lin
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Brain Keratan Sulfate and Glial Scar Formation
Annals of the New York Academy of Sciences, 2006Abstract: In response to injury to the central nervous system (CNS), reactive astrocytes appear and accumulate in the wounded area, leading to glial scar formation. Glial scar is the physical barrier to axonal regeneration of injured neurons. Chondroitin sulfate proteoglycans are inhibitory to axon outgrowth and are upregulated in reactive astrocytes
Haoqian, Zhang +2 more
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