Results 231 to 240 of about 182,642 (309)

A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders. [PDF]

Exp Dermatol
Salois MN, Webb S, Proctor IA, Koch PJ, Koster MI.   +4 more
europepmc   +1 more source

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

JEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson, Kara Hurley, Hannah Chaudhury, Lara Shehadeh, Cameron West   +4 more
wiley   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

Remodeling of the cell membrane-associated protein pool affects adhesive membrane properties in filaggrin insufficient keratinocytes and impacts distinct cellular and organellar functions. [PDF]

BMC Biol
Kobiela A, Klimczuk M, Serafin PK, Kitowska K, Biernacka A, Abouali R, de la Serna JB, Wang X, Gajdowska F, Kosobucka A, Siedlar AM, Hauer A, Hovhannisyan L, Bogucka A, Smits JPH, van den Bogaard EH, Sądej R, Ogg GS, Gutowska-Owsiak D.   +18 more
europepmc   +1 more source

Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective

JEADV Clinical Practice, EarlyView.
ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto, Victoria Griffith, Samuel Stahly, Jere Mammino   +3 more
wiley   +1 more source

Benign, persistent, and invasive: mechanistic and translational approaches to middle‑ear cholesteatoma. [PDF]

Explor Target Antitumor Ther
Samara P, Athanasopoulos M, Athanasopoulos I.   +2 more
europepmc   +1 more source

Efficacy Evaluation of N-Acyl-Phytosphingosine Prepared from Marula Oil Derived Fatty Acids in Skin Barrier Repair. [PDF]

Clin Cosmet Investig Dermatol
Liu Z, Zhu H, Yang Y, Chang H.
europepmc   +1 more source

Comparative Effects of Two Hyaluronic Acid-Based Formulations on Cellular Repair Mechanisms in Human Keratinocytes. [PDF]

Int J Mol Sci
Chmielewski R, Lebiedowska A.
europepmc   +1 more source

Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermis. [PDF]

Cell Death Discov
Schmidt MF, Feoktistova MA, Panayotova-Dimitrova D, Buhl EM, Boor P, Ruhl T, Waschke J, Tikkanen R, Röcken M, Baron JM, Yazdi AS.   +10 more
europepmc   +1 more source