Results 91 to 100 of about 1,560,167 (291)

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants. [PDF]

, 2020
The Genotype-Tissue Expression (GTEx) resource has provided insights into the regulatory impact of genetic variation on gene expression across human tissues; however, thus far has not considered how variation acts at the resolution of the different cell ...
D'Antonio, Matteo, D'Antonio-Chronowska, Agnieszka, Donovan, Margaret KR, Frazer, Kelly A   +3 more
core  

Lifetime prevalence of non-melanoma and melanoma skin cancer in Australian recreational and competitive surfers [PDF]

, 2016
Background/Purpose Surfing is one of the most popular outdoor aquatic activities in Australia with an estimated 2.7 million recreational surfers; however, Australia has long been recognized as having the highest incidence of melanoma in the world, and it ...
Climstein, Mike, Furness, James, Hing, Wayne, Walsh, Joe   +3 more
core   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

An overview of cutaneous squamous cell carcinoma imaging diagnosis methods

Frontiers in Medicine
Cutaneous squamous cell carcinoma, a type of non-melanoma skin cancer, is a form of keratinocyte carcinoma that stands as one of the most prevalent cancers, exhibiting a rising frequency.
Sorina Danescu, Mircea Negrutiu, Monica Focsan, Monica Focsan, Adrian Baican   +4 more
doaj   +1 more source

Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas

Genes and Diseases, 2021
The majority of non-melanoma skin cancer (NMSC) is cutaneous basal cell carcinoma (BCC) or squamous cell carcinoma (SCC), which are also called keratinocyte carcinomas, as both of them originate from keratinocytes.
Jun Wan, Hongji Dai, Xiaoli Zhang, Sheng Liu, Yuan Lin, Ally-Khan Somani, Jingwu Xie, Jiali Han   +7 more
doaj   +1 more source

Stromal control of oncogenic traits expressed in response to the overexpression of GLI2, a pleiotropic oncogene. [PDF]

, 2009
Hedgehog signaling is often activated in tumors, yet it remains unclear how GLI2, a transcription factor activated by this pathway, acts as an oncogene. We show that GLI2 is a pleiotropic oncogene.
Albertson, DG, Connelly, ST, Huey, B, Jordan, RCK, Roy, R, Schmidt, BL, Snijders, AM   +6 more
core  

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice [PDF]

, 2007
Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target.
Adriana Albini, Aggarwal BB, Aggarwal S, Airola K, Albini A, Albini A, Ammon HP, Andreas Nerlich, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Balduyck M, Banerji A, Beatrice Bachmeier, Benbow U, Benbow U, Bharti AC, Biswas DK, Cailleau R, Cailleau R, Chen H, Chen Z, Commandeur JN, Cristina Iancu, Divya CS, Erwin Schleicher, Garg A, Hahm ER, Hong JH, Hozumi A, Huang MT, Hunter KW, Ichiki K, Kawamori T, Kossakowska AE, Kuo ML, Li L, Limtrakul P, Manna SK, Marianne Jochum, Meade-Tollin LC, Mehta K, Menon LG, Menon LG, Michele Cilli, Mukaida N, Nagabhushan M, Nakshatri H, Netzker R, Noel A, Ohashi Y, Park AM, Park CH, Philip S, Raffaella Dell'Eva, Roberta Vené, Shao ZM, Stetler-Stevenson WG, Tetu B, Ulrich Pfeffer, Vincenti MP, Vincenti MP, Vincenti MP, Westermarck J, Wu JT, Yu G, Zhang RD   +70 more
core   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source