Results 111 to 120 of about 1,560,167 (291)

Metformin use and keratinocyte carcinoma risk [PDF]

Journal of the American Academy of Dermatology, 2021
Misitzis, Angelica, Weinstock, Martin A.
openaire   +3 more sources

Keratinocyte Transglutaminase Expression Varies in Squamous Cell Carcinomas

Journal of Investigative Dermatology, 1994
Type I transglutaminase (TGase I, keratinocyte or particulate transglutaminase) is a 92-kilodalton (kDa) protein expressed in abundance in cultured keratinocytes and in the hyperproliferative skin disorder psoriasis. To determine the expression of TGase I protein and mRNA, we studied tissue and established squamous carcinoma lines derived from ...
Duvic, Madeleine, Nelson, Deidra Chema, Annarella, Mary, Cho, Mimi, Esgleyes-Ribot, Teresa, Remenyik, E.v.a., Ulmer, Roseann, Rapini, Ronald P, Sacks, Peter G, Clayman, Gary L, Davies, Peter JA, Thacher, Scott   +11 more
openaire   +2 more sources

Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective

JEADV Clinical Practice, EarlyView.
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek, Iris Zalaudek, Karolina Zarańska, Bożena Cybulska‐Stopa   +3 more
wiley   +1 more source

Switch from alpha v beta 5 to alpha v beta 6 integrin expression protects squamous cell carcinomas from anoikis [PDF]

, 2004
Stratified squamous epithelia express the alphavbeta5 integrin, but in squamous cell carcinomas (SCCs) there is down-regulation of alphavbeta5 and up-regulation of alphavbeta6.
Janes, SM, Watt, FM
core  

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray, Robin Caird, Michael O'Connor, Ciara Drumm, Emma O'Hora, Franklin Crossen, Aoife Lally, Aurelie Fabre, Roisin Dolan   +8 more
wiley   +1 more source

Dermoscopy and methyl aminolevulinate: A study for detection and evaluation of field cancerization [PDF]

, 2016
Actinic keratosis (AK) is a keratinocyte intraepidermal neoplasia UV light – induced that frequently appears in sun-exposed areas of the skin. Although historically AK was de fi ned as “ precancerous ” , actually it is considered as the ...
Anzalone, Alessia, Cardone, Michele, Carlesimo, Marta, De Vita, G., Di Nunno, D., Fortuna, MARIA CATERINA, Garelli, Valentina, Mari, Elena, Pranteda, Giulia, Rossi, Alfredo   +9 more
core   +1 more source

Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin

Nature Communications, 2018
Cutaneous squamous cell carcinoma (cSCC) is a skin cancer that normally progresses from UV-induced actinic keratosis (AK). Here, the authors investigate the epigenomics of cSCC and highlight two distinct subclasses of AK and cSCC originating from ...
Manuel Rodríguez-Paredes, Felix Bormann, Günter Raddatz, Julian Gutekunst, Carlota Lucena-Porcel, Florian Köhler, Elisabeth Wurzer, Katrin Schmidt, Stefan Gallinat, Horst Wenck, Joachim Röwert-Huber, Evgeniya Denisova, Lars Feuerbach, Jeongbin Park, Benedikt Brors, Esther Herpel, Ingo Nindl, Thomas G. Hofmann, Marc Winnefeld, Frank Lyko   +19 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Recent Changes in the Incidence and Characteristics of Cutaneous Squamous Cell Carcinomas in Finland from 2006 to 2020: A Retrospective Cohort Study

Acta Dermato-Venereologica
Registers recording only 1 tumour per patient do not enable assessment of the real burden of cutaneous squamous cell carcinoma. To investigate recent changes in the incidence and characteristics of tumours, a retrospective 15-year patient cohort study ...
Marika Lounas, Leea Ylitalo, Teea Salmi, Juha Jernman, Johanna Palve, Tiina Luukkaala, Niina Korhonen   +6 more
doaj   +1 more source

Improved keratinocyte carcinoma outcomes with annual dermatology assessment after solid organ transplantation: Population‐based cohort study

American Journal of Transplantation, 2018
Solid organ transplant recipients have a high risk of keratinocyte carcinoma (non‐melanoma skin cancer). Consensus‐based transplant guidelines recommend annual dermatological examination but the impact on skin cancer–related outcomes is unclear.
A. Chan, K. Fung, Peter C. Austin, S. J. Kim, L. Singer, Nancy N. Baxter, R. Alhusayen, Paula A. Rochon   +7 more
semanticscholar   +1 more source