Results 121 to 130 of about 1,560,167 (291)

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

PROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren, Kenneth Weke, Darryl Hardie, Mariya I. Goncheva, Ted Hupp, Javier Antonio Alfaro, Helena Pětrošová, David R. Goodlett   +7 more
wiley   +1 more source

Comparison of the miRNA profiles in HPV-positive and HPV-negative tonsillar tumors and a model system of human keratinocyte clones [PDF]

, 2016
Background Better insights into the molecular changes involved in virus-associated and -independent head and neck cancer may advance our knowledge of HNC carcinogenesis and identify critical disease biomarkers.
Grega, Marek, Klozar, Jan, Prochazka, Bohumir, Sabol, Ivan, Salakova, Martina, Smahelova, Jana, Tachezy, Ruth, Turek, Lubomir, Vojtechova, Zuzana, Zavadil, Jiri   +9 more
core   +9 more sources

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Cell membrane‐coated nanoparticles for dermatological diseases

VIEW, EarlyView.
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley   +1 more source

Quercetin Inhibits Cell Survival and Metastatic Ability via the EMT-Mediated Pathway in Oral Squamous Cell Carcinoma

Molecules, 2020
This study aimed to investigate whether quercetin exerts anticancer effects on oral squamous cell carcinoma (OSCC) cell lines and to elucidate its mechanism of action.
So Ra Kim, Eun Young Lee, Da Jeong Kim, Hye Jung Kim, Hae Ryoun Park   +4 more
doaj   +1 more source

HLA-G: expression in human keratinocytes in vitro and in human skin in vivo [PDF]

, 1994
Classical, polymorphic major histocompatibility complex class I molecules are expressed on most nucleated cells.They present peptides at the cell surface and, thus, enable the immune system to scan peptides for their antigenicity.
Ulbrecht, M., Rehberger, B., Strobel, I., Messer, Gerald, Kind, P., Degitz, K., Bieber, T., Weiss, Elisabeth H.   +7 more
core   +2 more sources

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

Rates of Self‐Reported Skin Cancer in Current and Retired Elite Australian Cricketers

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background Skin cancer rates are high in Australians, outdoor workers and physically active people. Australia is currently preparing a roadmap to better assess high risk groups for consideration of more targeted skin screening. Methods The membership of the Australian Cricketers Association (ACA), both current and retired cricketers, was ...
John W. Orchard, Georgia Redmayne, Brad Stenner, Alex J. Chamberlain, Andrew Ming, Philippa Inge, Leona Yip   +6 more
wiley   +1 more source

Mapping the Current Demand and Supply of Dermatologists and General Practitioners Managing Skin Cancer in Queensland, Australia

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives The rising incidence of skin cancer places a significant burden on Australia's health workforce. To support workforce planning, we estimated the supply of dermatologists and general practitioners (GP) working in skin cancer medicine, service demand and need across Queensland in 2023.
Daniel Lindsay, Shaun Stangl, Kiana Ronagh, Jessica Cameron, Richard Johns, Jim Muir, Louisa G. Collins   +6 more
wiley   +1 more source

Occupational Sun Exposure and Melanoma Development: A Review of the Evidence

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Cutaneous melanomas arise through a number of causal pathways, all of which involve exposure to sunshine or artificial ultraviolet (UV) radiation to some extent. Their initiation also depends on host factors that determine susceptibility to melanoma, and whether the UV exposure is intermittent or chronic.
David C. Whiteman, Gabrielle J. Williams, John F. Thompson   +2 more
wiley   +1 more source