Results 141 to 150 of about 639,835 (244)

Keratinocyte Carcinoma Risk: Antithymocyte Globulin vs. Other Induction Therapy in Solid Organ Transplant Patients

open access: yes
BACKGROUND Induction immunosuppression reduces early rejection after solid organ transplantation but may increase long-term malignancy risk, including keratinocyte carcinoma.
Mary Rojas   +4 more
core   +1 more source

Male genital lichen sclerosus

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas   +3 more
wiley   +1 more source

Predicting Malignant Transformation in Oral Epithelial Dysplasia: A Systematic Comparison of Artificial Intelligence‐Based Risk Models and Pathologist‐Based Microscopy

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background/Aims Risk prediction models (RPMs) based on histopathological analysis of oral epithelial dysplasia (OED) are increasingly used to stratify patients with oral potentially malignant disorders (OPMDs) and support personalized management.
Diele Carine Barreto Arantes   +4 more
wiley   +1 more source

Long‐Term Care of OLP Patients: A Retrospective Study From a Single Hospital Outpatient Clinic

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated disorder with malignant potential. However, its real‐world clinical course remains incompletely characterized. This study aimed to describe the natural clinical–histopathological trajectory of OLP in a single tertiary centre and to identify factors associated with dysplasia and ...
F. Scilla   +8 more
wiley   +1 more source

Viruses, Periodontitis, and Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte   +2 more
wiley   +1 more source

Transcriptome Analysis Reveals Distinct Molecular Signatures Between Erosive and Non‐Erosive Oral Lichen Planus

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen   +5 more
wiley   +1 more source

Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia

open access: yesOral Diseases, EarlyView.
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio   +8 more
wiley   +1 more source

UV Exposure and the Risk of Keratinocyte Carcinoma in Skin of Color: A Systematic Review.

open access: yesJAMA Dermatol, 2022
Kolitz E   +5 more
europepmc   +1 more source

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