Epigenetic Alterations in Keratinocyte Carcinoma. [PDF]
J Invest Dermatol, 2021 Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are both derived from epidermal keratinocytes but phenotypically diverge. To improve understanding of keratinocyte carcinogenesis, it is critical to understand epigenetic alterations ...
Yao Q +7 more
europepmc +4 more sources
Genetic and environmental factors underlying keratinocyte carcinoma risk. [PDF]
JCI Insight, 2020 Recent large-scale GWAS and large epidemiologic studies have accelerated the discovery of genes and environmental factors that contribute to the risk of keratinocyte carcinoma (KC), which includes basal cell carcinoma (BCC) and squamous cell carcinoma ...
Choquet H +4 more
europepmc +5 more sources
Incidence and mortality rates of keratinocyte carcinoma from 1998-2017: a population-based study of sex differences in Ontario, Canada. [PDF]
CMAJ, 2021 Background: Keratinocyte carcinoma is the most common malignant disease, but it is not captured in major registries. We aimed to describe differences by sex in the incidence and mortality rates of keratinocyte carcinoma in Ontario, Canada.
Tang E, Fung K, Chan AW.
europepmc +2 more sources
Keratinocyte Carcinoma Incidence by Race and Ethnicity in Older Adults With Medicare Coverage.
JAMA Dermatol, 2023 This cohort study examines raw and age-adjusted differences in the incidence of keratinocyte carcinoma among Medicare beneficiaries by race and ethnicity.
Navsaria LJ +6 more
europepmc +2 more sources
Tumor Control Probability Modeling for Radiation Therapy of Keratinocyte Carcinoma. [PDF]
Front Oncol, 2021 Summary Skin cancer patients may be treated definitively using radiation therapy (RT) with electrons, kilovoltage, or megavoltage photons depending on tumor stage and invasiveness.
Prior P, Awan MJ, Wilson JF, Li XA.
europepmc +2 more sources
National trends in incidence and geographic distribution of melanoma and keratinocyte carcinoma in the Russian Federation [PDF]
Frontiers in Medicine, 2023 Keratinocyte Carcinomas (KC), including basal cell and cutaneous squamous cell carcinomas, are the most common skin cancers in Fitzpatrick phototype I-III individuals, while melanoma is one of the deadliest skin cancer types.
Anastasiya Muntyanu +5 more
doaj +2 more sources
Treatment of keratinocyte carcinoma in elderly patients - a review of the current literature. [PDF]
J Eur Acad Dermatol Venereol, 2020 A large percentage of the patients with keratinocyte carcinoma (KC, formerly known as non‐melanoma skin cancer) is of advanced age and often too frail for standard therapies.
Leus AJG +7 more
europepmc +2 more sources
JAMA Dermatol, 2021 Importance Topical calcineurin inhibitors (TCIs) are commonly used as second-line treatment for atopic dermatitis. In 2006, the US Food and Drug Administration issued a black box warning against TCI use, citing data from case reports and animal studies ...
Lam M, Zhu JW, Tadrous M, Drucker AM.
europepmc +2 more sources
Patients with Darier disease have an increased risk of keratinocyte carcinoma: a Swedish registry-based nationwide cohort study [PDF]
Orphanet Journal of Rare DiseasesBackground Darier disease is a genodermatosis which manifests as hyperkeratotic papules and superficial erosions mainly in seborrheic skin areas. This retrospective registry-based cohort study aimed to estimate the association between Darier disease and ...
Rahime Inci +4 more
doaj +2 more sources
A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision. [PDF]
Cancer Res, 2020 A fluorescent-probe-tumor-visualization platform was developed and validated in human keratinocyte carcinoma excision specimens that may provide simple, rapid, and global assessment of margins during skin cancer excision, allowing same-day reexcision ...
Walker E +16 more
europepmc +2 more sources