Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza +6 more
wiley +1 more source
Tetracycline reprograms inflammatory and regenerative signaling pathways in human keratinocytes exposed to <i>Loxosceles</i> spider venoms and sphingomyelinases. [PDF]
Front PharmacolPinto BF +6 more
europepmc +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak +11 more
wiley +1 more source
ML-driven quantum dots: novel HOXB13 imaging for porokeratosis with underlying squamous dysplasia associations. [PDF]
Ann Med Surg (Lond)Abbas Q, Johar MA, Umer M, Fatima M.
europepmc +1 more source
JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series
JEADV Clinical Practice, EarlyView.ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni +6 more
wiley +1 more source
Essential Role of Integrin-Linked Kinase in Keratinocyte Responses to Mechanical Strain. [PDF]
Int J Mol SciRudkouskaya A +3 more
europepmc +1 more source
Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan
JEADV Clinical Practice, EarlyView.Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi +4 more
wiley +1 more source
Konjac Ceramide Induces Semaphorin 3A Expression via the MAPK/AP-1 Signaling Axis and RORα in Normal Human Epidermal Keratinocytes. [PDF]
BiomoleculesFujita M +5 more
europepmc +1 more source
Desmosomal-Type Acantholysis-A New Histologic Pattern Related to Mutations of Genes for Desmosomal Proteins. [PDF]
Dermatopathology (Basel)Metze D +4 more
europepmc +1 more source
Early Acitretin Therapy in a Patient With Harlequin Ichthyosis
JEADV Clinical Practice, EarlyView.ABSTRACT Harlequin ichthyosis (HI) is a rare, severe congenital disorder of keratinization caused by pathogenic variants in the ABCA12 gene resulting in thick, hyperkeratotic plates, deep fissures, and characteristic facial and limb abnormalities.
Orasa Sukmark +2 more
wiley +1 more source