The role of Rho GTPases in facial morphogenesis
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Extracellular high mobility group box 1 as a UV-induced alarmin driving cutaneous inflammation and photoaging via TLR4 signaling. [PDF]
Liufu Q +8 more
europepmc +1 more source
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová +5 more
wiley +1 more source
MIR31HG Modulates IL-4 Secretion by Keratinocytes and M2-Like Macrophage Polarization to Promote Local Immunosuppression in Condyloma Acuminata. [PDF]
Xie X, Liu L, Huang H, Cao Y, Gu Z.
europepmc +1 more source
Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma
Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley +1 more source
The skin-specific long non-coding RNA TEDAR orchestrates late epidermal differentiation via an ERK-KLF4 cytoplasmic regulatory axis. [PDF]
Das Mahapatra K +12 more
europepmc +1 more source
Under‐Explored Species, Breeds and Cell Types With Potential for Cultivated Meat Production
This graphical abstract illustrates how the strategic selection of overlooked cell lines from novel species and specific agricultural breeds can help overcome current manufacturing bottlenecks in cultivated meat production. The schematic links the concept of an ‘ideal cell line’ to four key bioprocessing and product advantages that can be optimised ...
William Gordon‐Petrovskii +6 more
wiley +1 more source
Herring roe oil exerts immunomodulatory effects on the IL-17/23 signaling axis in immune and skin cells as models for psoriasis. [PDF]
Mildenberger J +7 more
europepmc +1 more source
ABSTRACT Background Robust outcome data for anterior skull base cutaneous squamous cell carcinoma (cSCC) are limited, particularly as emerging therapies reshape management. We evaluated survival and prognostic factors following craniofacial resection. Methods Retrospective multi‐institutional case‐series (1995–2015) of patients who underwent skull base
Michael J. C. Schachtel +52 more
wiley +1 more source
Integrative single-cell transcriptomic and epitranscriptomic analysis of the RBM15-m6A-IL10 regulatory axis in psoriatic keratinocytes. [PDF]
Li M, Jiang Y, Zhu C, Zhao M, Wang D.
europepmc +1 more source

