Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang +5 more
wiley +1 more source
Restraint of melanoma progression by cells in the local skin environment. [PDF]
Ma Y +9 more
europepmc +1 more source
Abstract Background Surface decontamination is integral to peri‐implantitis treatment. However, abrasive mechanical methods can cause implant surface degradation with possible adverse biological effects. No human studies have examined whether these treatments cause titanium release or impair regenerative outcomes.
Georgios A. Kotsakis +5 more
wiley +1 more source
Conditioned Medium from Irradiated Keratinocytes as a Tool for Investigating Communication within the Melano-epidermal Unit. [PDF]
Zortéa L +3 more
europepmc +1 more source
Aquaporin 3 Promoter Polymorphisms Reduce Gene Expression and Associate Altered Autophagy-Related Gene Signatures With Atopic Dermatitis Susceptibility. [PDF]
Lim YYE +5 more
europepmc +1 more source
ABSTRACT Striae distensae are common dermal lesions that negatively affect skin appearance, and topical management remains limited by challenges related to skin deposition and residence time. Here, we developed transparent surfactant‐based isotropic systems for the topical co‐delivery of ascorbic acid (AA), retinoic acid (RA), and lavender essential ...
Claudiane Ayres Prochno +8 more
wiley +1 more source
Novel dermis niche equivalent based on a 3D-structure fabricated by 2-photon polymerization. [PDF]
Schröder S +5 more
europepmc +1 more source
The effects of royal jelly on human health: A narrative review of clinical studies
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras +2 more
wiley +1 more source
A bioinformatic single-cell and structure-informed framework identifies a baicalin-CA2-keratinocyte state axis in atopic dermatitis. [PDF]
Yang B, Zhou G, Dai J.
europepmc +1 more source

