Results 21 to 30 of about 26,538 (309)

Utility of Keratins as Biomarkers for Human Oral Precancer and Cancer

Life, 2022
Human oral cancer is the single largest group of malignancies in the Indian subcontinent and the sixth largest group of malignancies worldwide. Squamous cell carcinomas (SCC) are the most common epithelial malignancy of the oral cavity, constituting over
Milind Vaidya, Crismita Dmello, Saie Mogre   +2 more
doaj   +1 more source

Rhabdomyosarcoma of the skull with fusion and ALK and cytokeratin expression: a case report [PDF]

Journal of Pathology and Translational Medicine
Rhabdomyosarcoma (RMS) comprises of heterogeneous group of neoplasms that occasionally express epithelial markers on immunohistochemistry (IHC). We herein report the case of a patient who developed RMS of the skull with EWSR1 fusion and anaplastic ...
Hyeong Rok An, Kyung-Ja Cho, Sang Woo Song, Ji Eun Park, Joon Seon Song   +4 more
doaj   +1 more source

Significance of stress keratin expression in normal and diseased epithelia

iScience
Summary: A group of keratin intermediate filament genes, the type II KRT6A-C and type I KRT16 and KRT17, are deemed stress responsive as they are induced in keratinocytes of surface epithelia in response to environmental stressors, in skin disorders (e.g.
Erez Cohen, Craig N. Johnson, Rachael Wasikowski, Allison C. Billi, Lam C. Tsoi, J. Michelle Kahlenberg, Johann E. Gudjonsson, Pierre A. Coulombe   +7 more
doaj   +1 more source

Methods of keratin extraction from wool and hair and prospects of their application in biomedicine and bioengineering

Біологічні студії, 2019
The present article gives the overview of scientific information on the hair structure, the structural and functional properties of keratins, and methods of their extracting from the natural fibers.
V. V. Mykhaliuk, V. V. Havryliak
doaj   +1 more source

Evaluation of expression of Toll-Like Receptors 7 and 9, proliferation, and cytoskeletal biomarkers in plaque and guttate psoriasis: A pilot morphological study

European Journal of Histochemistry, 2021
This pilot study was aimed at comparing TLR7/TLR9 expression, cytoskeletal arrangement, and cell proliferation by indirect immunofluorescence in parallel lesional and non lesional skin samples of guttate psoriasis (PG) and psoriasis vulgaris (PV) in five
Francesca Prignano, Giulia Lombardo, Serena Indino, Federica Ricceri, Laura Cornaghi, Elena B. Donetti   +5 more
doaj   +1 more source

Obtaining human hair keratin-based films and their characteristics

Біологічні студії, 2021
Background. Keratins are natural biopolymers with a wide range of applications in the field of biotechnology. Materials and Methods. Extraction of keratins was performed by a modified Nakamura method using 250 mM DTT.
V. V. Mykhaliuk, V. V. Havryliak
doaj   +1 more source

Sedimentation Studies of Epidermal Keratins. Keratin A and Keratin B [PDF]

The Journal of Cell Biology, 1956
Electrophoretically homogeneous keratin A and keratin B were studied in the ultracentrifuge. Both preparations revealed two fractions: one which sedimented rapidly and another which sedimented slowly. This indicated that both preparations are heterogeneous with respect to particle size.
openaire   +2 more sources

Human hair keratins

Journal of Investigative Dermatology, 1993
Human hair keratins were among the first to be studied but it is only recently that sufficient information has been obtained to gain a basic biologic perspective of these proteins. Hair keratins are members of the intermediate filament family of proteins, yet are sufficiently divergent from epidermal keratins to warrant separate classification: type Ia
J, Yu, D W, Yu, D M, Checkla, I M, Freedberg, A P, Bertolino   +4 more
openaire   +2 more sources

Bioprospecting keratinous materials

International Journal of Trichology, 2010
The concept of bioprospecting for bioactive peptides from keratin-containing materials such as wool, hair, skin and feathers presents an exciting opportunity for discovery of novel functional food ingredients and nutraceuticals, while value-adding to cheap and plentiful natural sources. The published literature reports multiple examples of proline-rich
Jones, LN, Sinclair, RD, Carver, J, Ecroyd, H, Lui, Y, Bennett, LE   +5 more
openaire   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source