Bilirubin-Induced Transcriptomic Imprinting in Neonatal Hyperbilirubinemia
Biology, 2023 Recent findings indicated aberrant epigenetic control of the central nervous system (CNS) development in hyperbilirubinemic Gunn rats as an additional cause of cerebellar hypoplasia, the landmark of bilirubin neurotoxicity in rodents.
John Paul Llido +7 more
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Severe Neonatal Hyperbilirubinemia; Causes and Contributing Factors Leading to Exchange Transfusion at Ghaem Hospital in Mashhad [PDF]
Acta Medica Iranica, 2010 Hyperbilirubinemia is common in neonates; it can have a serious rising course. Due to its critical morbidity called "kernicterus", severe neonatal hyperbilirubinemia causes which lead to exchange transfusion, should be clarified.
Farhad Heydarian, Mina Majdi
doaj +1 more source
Demystifying non-invasive approaches for screening jaundice in low resource settings: a review
Frontiers in Pediatrics, 2023 All national and international pediatric guidelines universally prescribe meticulous bilirubin screening for neonates as a critical measure to mitigate the incidence of acute bilirubin encephalopathy (ABE) and Kernicterus.
Umme Abiha +3 more
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A Bayesian Belief Network approach for predicting kernicterus [PDF]
, 2019 A lot of research have been conducted using expert systems in the diagnosis of neonatal jaundice but none has been conducted on kernicterus. Kernicterus is a complication of neonatal jaundice in which bilirubin accumulates in the grey matter of the brain,
Amadin, F.I., Bello, M.E.
core +2 more sources
Bilirubin-Induced Neurological Damage: Current and Emerging iPSC-Derived Brain Organoid Models
Cells, 2022 Bilirubin-induced neurological damage (BIND) has been a subject of studies for decades, yet the molecular mechanisms at the core of this damage remain largely unknown.
Abida Islam Pranty +2 more
doaj +1 more source
Electromyographic Characterization in an Animal model of Dystonia [PDF]
, 2008 Kernicterus causes damage to the auditory system and the basal ganglia in humans. Although the Gunn rat model of kernicterus has been extensively used to characterize the auditory features, this model has not been utilized to systematically investigate ...
Chaniary, Kunal Dilip
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Kernicterus in a Neonatal Foal [PDF]
Journal of Veterinary Diagnostic Investigation, 2007 A 5-day-old Thoroughbred foal was submitted to the necropsy service at the University of Kentucky Livestock Disease Diagnostic Center. The foal had a clinical history of seizure activity and severe icterus. A complete blood count and serum chemistry analysis indicated that the foal was anemic (hematocrit, 16%), hyperbilirubinemic (45 mg/dl), and ...
J. F. Freestone +2 more
openaire +2 more sources
DIAGNOSIS AND MANAGEMENT OF HYPERIBILIRUBINEMIA IN THE NEONATE [PDF]
Romanian Journal of Pediatrics, 2008 Bilirubin-induced neurologic dysfunction can occur in term and near-term healty babies. The term babies who are unwell, the preterm neonates, and the infants who have multiple comorbidities constitute a group vulnerable to bilirubin neurotxicity.
Valeriu Popescu, Daniela Patrichi
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Maternal and neonatal risk factors for neonatal jaundice and readmission – An Indian perspective
Acta Medica International, 2021 Introduction: Neonatal hyperbilirubinemia is a common neonatal ailment and is mostly benign except in few cases where it might progress to kernicterus.
Navjot Kaur +3 more
doaj +1 more source
Total and Fractionated Bilirubin during the First Week in the Neonatal Intensive Care Unit [PDF]
, 2014 Background. Fractionated bilirubin requires more blood (0.6 ml) than total bilirubin alone (0.2 ml). Our focus during the first week in the Neonatal Intensive Care Unit (NICU) is on prevention of Bilirubin Induced Neurologic Dysfunction and kernicterus ...
Ahlers-Schmidt, Carolyn R +2 more
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