Results 41 to 50 of about 26,568 (229)
In vitro and in vivo ketoconazole sensitivity disparity in a cutaneous candidiasis case of Kluyveromyces marxianus: A case report [PDF]
Introduction: Cutaneous candidiasis is an infection caused by the yeast, Candida albicans or other Candida-related species. Recently, Candida infections of the skin have become more prevalent and could be attributed to an increase in the number of ...
Chioma Nnenna Nwofor
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Bioequivalency Study of Two Formulations of Ketoconazole Tablet in Healthy Volunteers: Bioequivalenecy of ketoconazole tablets [PDF]
, 2005 In this study, the pharmacokinetic parameters of two marketed tablet formulations of ketoconazole were studied, and the relative bioavailability of the test formulation was compared with a reference formulation.
Sadeghnia, Hamid R. +1 more
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Comparison of three fluorescent CYP3A substrates in two vertebrate models: pig and Atlantic salmon
Animal, 2012 We investigated in vitro inhibitory effects of ketoconazole (KTZ) on cytochrome P450 activity in microsomes from pigs and Atlantic salmon. The following enzymatic reactions were studied: 7-benzyloxyresorufin and 7-ethoxyresorufin O-dealkylation (BROD and
V. Zlabek, G. Zamaratskaia
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British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson +8 more
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Livarol in the treatment of chronic vulvovaginal candidiasis
Репродуктивная эндокринология, 2017 The article presents the results of the study of treatment of women with chronic vulvovaginal candidiasis by vaginal suppositories Livarol, which contain 400 mg of ketoconazole. Treatment was carried out according to two schemes.
Т. С. Дивакова +1 more
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Pharmaceutics, 2021 Ketoconazole (KET), a synthetic imidazole broad-spectrum antifungal agent, is characterized by its poor aqueous solubility and high molecular weight, which might hamper its corneal permeation.
Tarek A. Ahmed +3 more
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BMEMat, EarlyView.Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu +7 more
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Evaluation of ketoconazole as a treatment for Cushing’s disease in a retrospective cohort
Frontiers in Endocrinology, 2022 ObjectiveThe first-line treatment for Cushing’s disease is transsphenoidal surgery, after which the rates of remission are 60 to 80%, with long-term recurrence of 20 to 30%, even in those with real initial remission.
Camila Viecceli +10 more
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BMEMat, EarlyView.Inorganic sonosensitizers suffer from inefficient electron‐hole separation, rapid recombination, and wide bandgaps in anti‐fungal applications. We propose MN@Fe2N/CeO2 to directly eliminate fungi without drug resistance. Combining semiconductor CeO2's advantages with Fe2N's high work function and activity enables efficient Schottky heterojunctions ...
Li Wang +13 more
wiley +1 more source
Massive Hepatic Enlargement with Fatty Change Associated with Ketoconazole [PDF]
, 1990 Several forms of hepatic toxicity have been described with the antifungal agent ketoconazole. We report a case of massive liver enlargement with fatty infiltration presenting as gastric compression.
Douglas V. Sepkowitz, Jeremy D. Gradon
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