Multifactorial Mechanisms of Tolerance to Ketoconazole in Candida albicans
Candida albicans is a prevalent opportunistic human fungal pathogen for which treatment is limited to only four main classes of antifungal drugs, with the azole and echinocandin classes being used most frequently.
Yi Xu +6 more
doaj +1 more source
Background Increase in resistance to conventional antifungals renders the need for antifungal sensitivity testing in Dermatophytes. The present study aimed at determining the prevalence of dermatophytic infections and their susceptibility ...
Dharmendra Singh +4 more
doaj +1 more source
A novel formulation of ketoconazole entrapped in alginate with anionic polymer beads for solubility enhancement: Preparation and characterization [PDF]
Ketoconazole has low solubility in intestinal pH, whereas drug absorption is largest in the small intestine, which can reduce the bioavailability of the drug.
Viviane Annisa +3 more
doaj +3 more sources
Enhanced Interaction between Warfarin and High-Dose Ketoconazole: A Case Report
This case describes the increased anticoagulation effect associated with the use of high-dose ketoconazole. A 59-year-old man treated with warfarin for aortic valve replacement was prescribed high-dose ketoconazole and hydrocortisone for the treatment ...
Cynthia A. Jackevicius, Mannhu N. Ton
doaj +1 more source
Physiology-based IVIVE predictions of tramadol from in vitro metabolism data [PDF]
To predict the tramadol in vivo pharmacokinetics in adults by using in vitro metabolism data and an in vitro-in vivo extrapolation (IVIVE)-linked physiologically-based pharmacokinetic (PBPK) modeling and simulation approach (SimcypA (R)).
Allegaert, Karel +10 more
core +1 more source
Parathyroid localization [PDF]
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B. +7 more
core +1 more source
Characterization of pea starch-guar gum biocomposite edible films enriched by natural antimicrobial agents for active food packaging [PDF]
Antimicrobial activity of epigallocatechin-3-gallate (EGCG) and two native Australian plants blueberry ash (BBA) fruit and macadamia (MAC) skin extracts against nine pathogenic and spoilage bacteria and seven strains of fungi, using an agar well ...
Chockchaisawasdee, Suwimol +4 more
core +2 more sources
Modelling of Behavior for Inhibition Corrosion of Bronze Using Artificial Neural Network (ANN)
In this work, three models based on Artificial Neural Network (ANN) were developed to describe the behavior for the inhibition corrosion of bronze in 3.5% NaCl + 0.1 M Na2SO4, using the experimental data of Electrochemical Impedance Spectroscopy (EIS ...
D. Elusaí Millán-Ocampo +5 more
doaj +1 more source
Prospective evaluation of low-dose ketoconazole plus hydrocortisone in docetaxel pre-treated castration-resistant prostate cancer patients. [PDF]
BackgroundKetoconazole is a well-known CYP17-targeted systemic treatment for castration-resistant prostate cancer (CRPC). However, most of the published data has been in the pre-chemotherapy setting; its efficacy in the post-chemotherapy setting has not ...
Beckett, LA +6 more
core
Effects of Imipramine and Lithium on the Suppression of Cell Proliferation in the Dentate Gyrus of the Hippocampus in Adrenocorticotropic Hormone-treated Rats [PDF]
We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells.
Asanuma, Masato +9 more
core +1 more source

