Results 11 to 20 of about 26,503 (228)
Role of Topical Ketoconazole in Therapeutic Hair Care Beyond Seborrhoeic Dermatitis and Dandruff
JEADV Clinical PracticeKetoconazole shampoo has well‐documented consistent efficacy and safety in treating dandruff and seborrhoeic dermatitis (SD) when compared to other active antidandruff ingredients such as selenium sulphide, corticosteroids and zinc pyrithione.
Aditya K. Gupta +2 more
doaj +2 more sources
Does the circulating ketoconazole metabolite N-deacetyl ketoconazole contribute to the drug-drug interaction potential of the parent compound? [PDF]
, 2021 Ketoconazole is a strong inhibitor of cytochrome P450 3A4 (CYP3A4) and of P-glycoprotein (P-gp) and is often used as an index inhibitor especially for CYP3A4-mediated drug metabolism. A preliminary physiologically based pharmacokinetic (PBPK) model for
Foerster, Kathrin Isabelle +6 more
core +1 more source
Acta Veterinaria Scandinavica, 2021 Background Ketoconazole, an antifungal agent, adversely affects spermatogenesis in rodents, but knowledge on adverse effects of prolonged administration of ketoconazole on the fertility of male dogs is lacking.
Anna Domosławska, Sławomir Zduńczyk
doaj +1 more source
Protolytic equilibria in homogeneous and heterogeneous systems of ketoconazole and its direct spectrophotometric determination in tablets [PDF]
Journal of the Serbian Chemical Society, 2005 The acid-base equilibria of a diprotic, slightly hydrosoluble base ketoconazole were studied in homogeneous and heterogeneous water systems. The determinations were performed at 25ºC at a constant ionic strength of M(NaCl).
Vojić Mirjana P. +3 more
doaj +3 more sources
Pharmaceuticals, 2023 To improve the solubility and dissolution rate of the BCS class II drug ketoconazole, five novel solid forms in 1:1 stoichiometry were obtained upon liquid-assisted grinding, slurry, and slow evaporation methods in the presence of coformers, namely ...
Hongmei Yu +8 more
doaj +1 more source
Gynecomastia with Ketoconazole [PDF]
Antimicrobial Agents and Chemotherapy, 1981 Three of forty men developed bilateral gynecomastia upon ketoconazole treatment. Symptoms abated despite continued therapy. This appears to be a direct drug effect on breast tissue.
R, DeFelice, D G, Johnson, J N, Galgiani
openaire +2 more sources
Bioengineering & Translational Medicine, 2023 Ionic liquids (ILs) loading ketoconazole (KCZ) have shown better efficacy on rats with tinea pedis than the marketed Daktarin® but clinical studies are still lacking.
Xiying Wu +10 more
doaj +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Pharmaceutics, 2021 Ketoconazole (KET), a synthetic imidazole broad-spectrum antifungal agent, is characterized by its poor aqueous solubility and high molecular weight, which might hamper its corneal permeation.
Tarek A. Ahmed +3 more
doaj +1 more source
Evaluation of ketoconazole as a treatment for Cushing’s disease in a retrospective cohort
Frontiers in Endocrinology, 2022 ObjectiveThe first-line treatment for Cushing’s disease is transsphenoidal surgery, after which the rates of remission are 60 to 80%, with long-term recurrence of 20 to 30%, even in those with real initial remission.
Camila Viecceli +10 more
doaj +1 more source