Results 1 to 10 of about 26,503 (228)
Indonesian Journal of Pharmacy, 2021 The use of radiopharmaceuticals for infection detection has gained increasing attention for their application in nuclear medicine. The administration of [99mTc]Tc-ketoconazole may altere pharmacological aspects including interaction data with some ...
Ahmad Kurniawan +4 more
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Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 Cells. [PDF]
PLoS ONE, 2014 Antifungal drug ketoconazole causes severe drug-drug interactions by influencing gene expression and catalytic activity of major drug-metabolizing enzyme cytochrome P450 CYP3A4.
Aneta Novotná +6 more
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Ketoconazole-Loaded Mucoadhesive Nanoemulsions for the Better Management of Topical Fungal Infections: Optimization, In Vitro, Ex Vivo, and In Vivo Assessments [PDF]
PharmaceuticsBackground/Objective: The introduction of Ketoconazole (KZ, Nizoral®) in 1977 by Janssen Pharmaceutica marked a significant milestone in medical mycology as the first broad-spectrum oral antifungal agent.
Mashan Almutairi +4 more
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Impact of vaginal microbiota on the clinical efficacy and long-term recurrence of ketoconazole suppositories in treating severe vulvovaginal candidiasis: a secondary analysis of a multicentre randomised trial [PDF]
Frontiers in Cellular and Infection MicrobiologyObjectiveTo evaluate whether baseline vaginal-microbiota status influences the clinical cure rate and 30-day mycological recurrence of severe VVC after 6-day intravaginal ketoconazole therapy compared with miconazole nitrate.MethodsA prospective ...
Lan Mi, Dai Zhang
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The combination of amoxicillin-clavulanic acid and ketoconazole in the treatment of Madurella mycetomatis eumycetoma and Staphylococcus aureus co-infection. [PDF]
PLoS Neglected Tropical Diseases, 2014 Eumycetoma is a chronic progressive disabling and destructive inflammatory disease which is commonly caused by the fungus Madurella mycetomatis. It is characterized by the formation of multiple discharging sinuses.
Najwa A Mhmoud +3 more
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Journal of College of Medical Sciences-Nepal, 2021 Introduction: Many treatments have been attempted in pityriasis versicolor with different reports of success. No direct comparative study between Ketoconazole 400 mg single dose against Ketoconazole 200 mg od for 5 days have been made earlier. The aim of
Harendra Kumar Jha +2 more
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The Effect of Insulin induced Hypoglycemia on ketoconazole Hepatototxicity in Rabbit [PDF]
The Medical Journal of Basrah University, 2015 Background: Hypoglycemia is one of the most common side effect of insulin treatment, it affect liver and can potentiate ketoconazole toxicity. Objectives: To measure effect of ketoconazole on liver enzymes, hypoglycemic oxidative stress and to evaluate
Nabeel A.J.Ali, Riyad H. Zayer Anaed
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Al-Azhar Assiut Medical Journal, 2022 Background and aim Pityriasis versicolor is a common chronic superficial fungal infection that manifests during or after puberty in hot humid temperatures.
Khaled M Tawfik +2 more
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Frontiers in Endocrinology, 2023 IntroductionThe first-line treatment for Cushing’s disease is transsphenoidal surgery for pituitary tumor resection. Ketoconazole has been used as a second-line drug despite limited data on its safety and efficacy for this purpose.
Camila Viecceli +9 more
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