Results 21 to 30 of about 26,568 (229)

Qualitative and quantitative assessment of related substances in the Compound Ketoconazole and Clobetasol Propionate Cream by HPLC-TOF-MS and HPLC

open access: yesJournal of Pharmaceutical Analysis, 2019
Related substances in pharmaceutical formulations are associated with their safety, efficacy and stability. However, there is no overall study already published on the assessment of related substances in the Compound Ketoconazole and Clobetasol ...
Wenling Yang   +8 more
doaj   +1 more source

Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study

open access: yesMagna Medika, 2023
Trichophyton rubrum is type of fungus that most often causes superficial fungal infections. Development of herbal ingredients as antifungal therapy is carried out to find alternative therapies for fungal infections.
Vika Pangesty   +2 more
doaj   +1 more source

Ketoconazole Binds to the Human Androgen Receptor [PDF]

open access: yes, 1992
Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections ...
Eil, C.
core   +1 more source

Formulation and Evaluation of Ketoconazole Nano-suspension [PDF]

open access: yes, 2023
The use of antifungals that are widely used by the public is ketoconazole. Ketoconazole is included in the Biopharmaceutical Classification System (BCS) II category, where the drug is poorly soluble in water but has high permeability.
Gita Deslia Sari, Eriska Agustin
core   +2 more sources

Systemic absorption of ketoconazole from vaginal pessaries. [PDF]

open access: yes, 1984
Eight healthy female subjects were each given (a) ketoconazole 400 mg orally, (b) ketoconazole 400 mg as a single vaginal pessary, (c) ketoconazole 800 mg as two vaginal pessaries, and (d) ketoconazole 1200 mg as three vaginal pessaries.
MD Ene   +7 more
core   +1 more source

Protolytic equilibria in homogeneous and heterogeneous systems of ketoconazole and its direct spectrophotometric determination in tablets [PDF]

open access: yesJournal of the Serbian Chemical Society, 2005
The acid-base equilibria of a diprotic, slightly hydrosoluble base ketoconazole were studied in homogeneous and heterogeneous water systems. The determinations were performed at 25 ºC at a constant ionic strength of 0.1M(NaCl).
MIRJANA P. VOJIC   +3 more
doaj   +3 more sources

OPTIMIZATION AND EVALUATION OF TOPICAL KETOCONAZOLE NANOEMULSION [PDF]

open access: yes, 2018
 Objective: The present study is to formulate and optimization of surfactant, cosurfactant, and oil of ketoconazole nanoemulsion.Methods: Ketoconazole was dissolved in surfactant, cosurfactant, and oil until saturated, clear solution extracted with ...
Ramlan Sinaga, Kasmirul   +2 more
core   +4 more sources

Utilization of alginate with gum acacia/pectin/carrageenan as precipitation inhibitor to improve bioavailability in drug supersaturation: A case study of ketoconazole

open access: yesCarbohydrate Polymer Technologies and Applications, 2023
Weak base drugs tend to precipitate in the intestine, leading to a decrease in their bioavailability. Precipitation initiates with supersaturation due to a pH shift from the stomach to the small intestine.
Viviane Annisa   +3 more
doaj   +1 more source

Formulation and Evaluation of Liposomes of Ketoconazole [PDF]

open access: yes, 2009
Antifungal drug, Ketoconazole was encapsulated in liposomes for topical application. Ketoconazole liposomes were prepared by thin film hydration technique using soya lecithin, cholesterol and drug in different weight ratios.
Hardik Patel, Rakesh Patel, Ashok Baria
core   +1 more source

Ketoconazole Salt and Co-crystals with Enhanced Aqueous Solubility [PDF]

open access: yes, 2016
Crystal structures of ketoconazole oxalate salt (1) and three co-crystals with fumaric (2), succinic (3), and adipic (4) acids in 1:1 stoichiometry were determined by single-crystal X-ray diffraction in which 1 forms oxalate dimers involved in ionic ...
Xenia Filip (1904386)   +4 more
core   +3 more sources

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