Results 21 to 30 of about 26,568 (229)
Related substances in pharmaceutical formulations are associated with their safety, efficacy and stability. However, there is no overall study already published on the assessment of related substances in the Compound Ketoconazole and Clobetasol ...
Wenling Yang +8 more
doaj +1 more source
Trichophyton rubrum is type of fungus that most often causes superficial fungal infections. Development of herbal ingredients as antifungal therapy is carried out to find alternative therapies for fungal infections.
Vika Pangesty +2 more
doaj +1 more source
Ketoconazole Binds to the Human Androgen Receptor [PDF]
Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections ...
Eil, C.
core +1 more source
Formulation and Evaluation of Ketoconazole Nano-suspension [PDF]
The use of antifungals that are widely used by the public is ketoconazole. Ketoconazole is included in the Biopharmaceutical Classification System (BCS) II category, where the drug is poorly soluble in water but has high permeability.
Gita Deslia Sari, Eriska Agustin
core +2 more sources
Systemic absorption of ketoconazole from vaginal pessaries. [PDF]
Eight healthy female subjects were each given (a) ketoconazole 400 mg orally, (b) ketoconazole 400 mg as a single vaginal pessary, (c) ketoconazole 800 mg as two vaginal pessaries, and (d) ketoconazole 1200 mg as three vaginal pessaries.
MD Ene +7 more
core +1 more source
Protolytic equilibria in homogeneous and heterogeneous systems of ketoconazole and its direct spectrophotometric determination in tablets [PDF]
The acid-base equilibria of a diprotic, slightly hydrosoluble base ketoconazole were studied in homogeneous and heterogeneous water systems. The determinations were performed at 25 ºC at a constant ionic strength of 0.1M(NaCl).
MIRJANA P. VOJIC +3 more
doaj +3 more sources
OPTIMIZATION AND EVALUATION OF TOPICAL KETOCONAZOLE NANOEMULSION [PDF]
 Objective: The present study is to formulate and optimization of surfactant, cosurfactant, and oil of ketoconazole nanoemulsion.Methods: Ketoconazole was dissolved in surfactant, cosurfactant, and oil until saturated, clear solution extracted with ...
Ramlan Sinaga, Kasmirul +2 more
core +4 more sources
Weak base drugs tend to precipitate in the intestine, leading to a decrease in their bioavailability. Precipitation initiates with supersaturation due to a pH shift from the stomach to the small intestine.
Viviane Annisa +3 more
doaj +1 more source
Formulation and Evaluation of Liposomes of Ketoconazole [PDF]
Antifungal drug, Ketoconazole was encapsulated in liposomes for topical application. Ketoconazole liposomes were prepared by thin film hydration technique using soya lecithin, cholesterol and drug in different weight ratios.
Hardik Patel, Rakesh Patel, Ashok Baria
core +1 more source
Ketoconazole Salt and Co-crystals with Enhanced Aqueous Solubility [PDF]
Crystal structures of ketoconazole oxalate salt (1) and three co-crystals with fumaric (2), succinic (3), and adipic (4) acids in 1:1 stoichiometry were determined by single-crystal X-ray diffraction in which 1 forms oxalate dimers involved in ionic ...
Xenia Filip (1904386) +4 more
core +3 more sources

