Results 111 to 120 of about 9,766 (126)
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Journal of Clinical Oncology, 2019
e13558 Background: Glioblastoma (GBM) remains one of the most lethal primary brain tumors in children and adults. Despite enormous efforts to elucidate the genetic and epigenetic drivers of this disease, the prognosis for patients diagnosed with GBM remains dismal. Because tumor cell metabolism differs greatly from that of normal non-cancerous cells,
Frederic Anthony Vallejo +9 more
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e13558 Background: Glioblastoma (GBM) remains one of the most lethal primary brain tumors in children and adults. Despite enormous efforts to elucidate the genetic and epigenetic drivers of this disease, the prognosis for patients diagnosed with GBM remains dismal. Because tumor cell metabolism differs greatly from that of normal non-cancerous cells,
Frederic Anthony Vallejo +9 more
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Ketogenic Diet and Metabolic Therapies
2016Abstract Ketogenic diets have been used to treat epilepsy for nearly a century. Alongside enduring clinical success with a ketogenic diet, metabolism’s critical role in health and in diseases in the central nervous system and throughout the body is increasingly appreciated.
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Neurochemical Research, 2019
No major advances have been made in improving overall survival for glioblastoma (GBM) in almost 100 years. The current standard of care (SOC) for GBM involves immediate surgical resection followed by radiotherapy with concomitant temozolomide chemotherapy.
Thomas N, Seyfried +6 more
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No major advances have been made in improving overall survival for glioblastoma (GBM) in almost 100 years. The current standard of care (SOC) for GBM involves immediate surgical resection followed by radiotherapy with concomitant temozolomide chemotherapy.
Thomas N, Seyfried +6 more
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Abstract 6805: A ketogenic diet sensitizes pancreatic cancer to metabolic therapies
Cancer ResearchAbstract Background: Pancreatic cancer is the third leading cause of cancer-related death in the United States, and current chemotherapy options provide limited benefit. Recent studies have shown that a ketogenic diet (KD) can exert anti-tumor effects by reprogramming tumor metabolism and ...
Omid Hajihassani +16 more
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The FASEB Journal, 2016
Cancers exhibit an abnormal metabolism characterized by increased glucose consumption. Studies suggest that unlike healthy tissues, cancer cells are unable to efficiently utilize ketones for energy, a vulnerability exploited by a potential new therapy, the high fat low carbohydrate ketogenic diet (KD).
Angela Poff +3 more
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Cancers exhibit an abnormal metabolism characterized by increased glucose consumption. Studies suggest that unlike healthy tissues, cancer cells are unable to efficiently utilize ketones for energy, a vulnerability exploited by a potential new therapy, the high fat low carbohydrate ketogenic diet (KD).
Angela Poff +3 more
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Zhonghua wei zhong bing ji jiu yi xue, 2023
Heart failure (HF) has become a major challenge in the treatment of global cardiovascular diseases. Great progress has been made in the drug treatment of HF, however, rehospitalization rate and mortality of patients with HF are still high. Hence, there is an urgent need to explore new treatment strategy and new underlying pathogenic mechanisms.
Qiong, Wang +4 more
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Heart failure (HF) has become a major challenge in the treatment of global cardiovascular diseases. Great progress has been made in the drug treatment of HF, however, rehospitalization rate and mortality of patients with HF are still high. Hence, there is an urgent need to explore new treatment strategy and new underlying pathogenic mechanisms.
Qiong, Wang +4 more
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The Effect of Ketogenic Metabolic Therapy on Recurrent High-Grade Gliomas: Case Series
Journal of Neuro and Oncology ResearchHigh-grade gliomas represent the most prevalent primary malignant brain tumors in the adult population. Despite extensive efforts dedicated to advance in therapeutic modalities, treatment options remain very limited in this field, leading to a worse prognosis for affected patients.
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Ketogenic diet as a metabolic therapy for bipolar disorder: Clinical developments
Journal of Affective Disorders Reports, 2023Brenda Yu, Shebani Sethi
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The ketogenic diet: metabolic influences on brain excitability and epilepsy
Trends in Neurosciences, 2013Andrew Lutas, Gary Yellen
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