Results 121 to 130 of about 10,739 (204)
Additional file 4 of Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Supplementary Material 4.Duraj, Tomás, Kalamian, Miriam, Zuccoli, Giulio, Maroon, Joseph C., D’Agostino, Dominic P., Scheck, Adrienne C., Poff, Angela, Winter, Sebastian F., Hu, Jethro, Klement, Rainer J., Hickson, Alicia, Lee, Derek C., Cooper, Isabella, Kofler, Barbara, Schwartz, Kenneth A., Phillips, Matthew C. L., Champ, Colin E., Zupec-Kania, Beth, Tan-Shalaby, Jocelyn, Serfaty, Fabiano M., Omene, Egiroh, Arismendi-Morillo, Gabriel, Kiebish, Michael, Cheng, Richard, El-Sakka, Ahmed M., Pflueger, Axel, Mathews, Edward H., Worden, Donese, Shi, Hanping, Cincione, Raffaele Ivan, Spinosa, Jean Pierre, Slocum, Abdul Kadir, Iyikesici, Mehmet Salih, Yanagisawa, Atsuo, Pilkington, Geoffrey J., Chaffee, Anthony, Abdel-Hadi, Wafaa, Elsamman, Amr K., Klein, Pavel, Hagihara, Keisuke, Clemens, Zsófia, Yu, George W., Evangeliou, Athanasios E., Nathan, Janak K., Smith, Kris, Fortin, David, Dietrich, Jorg, Mukherjee, Purna, Seyfried, Thomas N. +48 moreopenaire +1 more sourceHistone Modifications at the Intersection of Aging, Neuroinflammation and Metabolism in Alzheimer's Disease
Aging Cell, Volume 25, Issue 11, November 2026.This review examines how histone modifications integrate aging, metabolic dysfunction and neuroinflammation to shape persistent, cell‐type‐specific chromatin states in Alzheimer's disease. By distinguishing causal regulation from association through perturbation, persistence and reversibility, it highlights metabolic–epigenetic feedback loops and ...Junyi Liang, Huawen Cao, Xiumin Ren, Nan Sha, Xueqing Han, Ling Jiang, Bin Liu, Weiming Zhao +7 morewiley +1 more sourceAdditional file 7 of Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Supplementary Material 7.Duraj, Tomás, Kalamian, Miriam, Zuccoli, Giulio, Maroon, Joseph C., D’Agostino, Dominic P., Scheck, Adrienne C., Poff, Angela, Winter, Sebastian F., Hu, Jethro, Klement, Rainer J., Hickson, Alicia, Lee, Derek C., Cooper, Isabella, Kofler, Barbara, Schwartz, Kenneth A., Phillips, Matthew C. L., Champ, Colin E., Zupec-Kania, Beth, Tan-Shalaby, Jocelyn, Serfaty, Fabiano M., Omene, Egiroh, Arismendi-Morillo, Gabriel, Kiebish, Michael, Cheng, Richard, El-Sakka, Ahmed M., Pflueger, Axel, Mathews, Edward H., Worden, Donese, Shi, Hanping, Cincione, Raffaele Ivan, Spinosa, Jean Pierre, Slocum, Abdul Kadir, Iyikesici, Mehmet Salih, Yanagisawa, Atsuo, Pilkington, Geoffrey J., Chaffee, Anthony, Abdel-Hadi, Wafaa, Elsamman, Amr K., Klein, Pavel, Hagihara, Keisuke, Clemens, Zsófia, Yu, George W., Evangeliou, Athanasios E., Nathan, Janak K., Smith, Kris, Fortin, David, Dietrich, Jorg, Mukherjee, Purna, Seyfried, Thomas N. +48 moreopenaire +1 more sourceClinical and genetic characterization of intellectual disability
Developmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1601-1609, November 2026.This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala +14 morewiley +1 more sourceAdditional file 1 of Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Supplementary Material 1.Duraj, Tomás, Kalamian, Miriam, Zuccoli, Giulio, Maroon, Joseph C., D’Agostino, Dominic P., Scheck, Adrienne C., Poff, Angela, Winter, Sebastian F., Hu, Jethro, Klement, Rainer J., Hickson, Alicia, Lee, Derek C., Cooper, Isabella, Kofler, Barbara, Schwartz, Kenneth A., Phillips, Matthew C. L., Champ, Colin E., Zupec-Kania, Beth, Tan-Shalaby, Jocelyn, Serfaty, Fabiano M., Omene, Egiroh, Arismendi-Morillo, Gabriel, Kiebish, Michael, Cheng, Richard, El-Sakka, Ahmed M., Pflueger, Axel, Mathews, Edward H., Worden, Donese, Shi, Hanping, Cincione, Raffaele Ivan, Spinosa, Jean Pierre, Slocum, Abdul Kadir, Iyikesici, Mehmet Salih, Yanagisawa, Atsuo, Pilkington, Geoffrey J., Chaffee, Anthony, Abdel-Hadi, Wafaa, Elsamman, Amr K., Klein, Pavel, Hagihara, Keisuke, Clemens, Zsófia, Yu, George W., Evangeliou, Athanasios E., Nathan, Janak K., Smith, Kris, Fortin, David, Dietrich, Jorg, Mukherjee, Purna, Seyfried, Thomas N. +48 moreopenaire +1 more sourceCiliary Membrane Lipid Homeostasis in Health and Disease
Advanced Science, Volume 13, Issue 58, 19 October 2026.This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu +3 morewiley +1 more sourceMetabolic Structure: A Paradigm Revisited in Light of the Fundamental Parameters of Living Systems
BioEssays, Volume 48, Issue 10, October 2026.Metabolism is redefined as a dynamic thermodynamic field shaped by six fundamental parameters (time, water, entropy, quantum effects, space, and electrostatics) rather than fixed genetic architecture. Case studies from enzyme kinetics to cancer cell differentiation show metabolic states, not structure alone, determine flux and control, and can be ...Jacques Fantiniwiley +1 more sourceKetogenic Diet–Associated Remodeling of the Cortical Proteome in Rats With Genetic Absence Epilepsy
Brain and Behavior, Volume 16, Issue 10, October 2026.Proteomic profiling of the somatosensory cortex revealed that ketogenic diet was associated with remodeling of cortical protein networks in GAERS absence epilepsy, with altered proteins enriched in synaptic and mitochondrial pathways. ABSTRACT Purpose
This study investigated the effects of ketogenic diet (KD) intervention on the cortical proteome in ...Aslihan Gunel, Ulku Guler, Aylin Toplu, Nazli Busra Acikgoz, Bora Onat, Ariorad Moniri, Bekir Salih, Osman Ugur Sezerman, Filiz Onat +8 morewiley +1 more source
