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[Macrolides, ketolides and streptogramins].
Enfermedades infecciosas y microbiologia clinica, 2003Macrolides, ketolides and streptogramins are three families of antibiotics with different chemical structures, sharing the same mechanism of action. All three bind to distinct bases of the peptidyl transferase center of ARNr 23S. Their antibacterial spectrum practically overlaps, but dissimilarities in affinity and/or number of binding sites determine ...
José, Mensa +2 more
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Macrolides and ketolides: azithromycin, clarithromycin, telithromycin
Infectious Disease Clinics of North America, 2004The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This
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Macrolides, Azalides, and Ketolides
2011The macrolides and azalides are a generally well-tolerated class of antimicrobials used to treat several mild-to-moderate infections associated with Gram-positive microorganism. Over 50 years of clinical experience with the macrolides has also led to the observation of non-antimicrobial properties that are now being exploited in clinical practice.
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A Journey Across the Sequential Development of Macrolides and Ketolides Related to Erythromycin
Tetrahedron, 2006Sarbani Pal
exaly
New Research in Macrolides and Ketolides Since 1997
Expert Opinion on Investigational Drugs, 1999André Bryskier, A Bryskier
exaly

