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[Macrolides, ketolides and streptogramins].

Enfermedades infecciosas y microbiologia clinica, 2003
Macrolides, ketolides and streptogramins are three families of antibiotics with different chemical structures, sharing the same mechanism of action. All three bind to distinct bases of the peptidyl transferase center of ARNr 23S. Their antibacterial spectrum practically overlaps, but dissimilarities in affinity and/or number of binding sites determine ...
José, Mensa   +2 more
openaire   +1 more source

Macrolides and ketolides: azithromycin, clarithromycin, telithromycin

Infectious Disease Clinics of North America, 2004
The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This
openaire   +2 more sources

Macrolides, Azalides, and Ketolides

2011
The macrolides and azalides are a generally well-tolerated class of antimicrobials used to treat several mild-to-moderate infections associated with Gram-positive microorganism. Over 50 years of clinical experience with the macrolides has also led to the observation of non-antimicrobial properties that are now being exploited in clinical practice.
openaire   +1 more source

Macrolide, Azalide, and Ketolides

2007
Sanjay Jain   +2 more
openaire   +2 more sources

New Research in Macrolides and Ketolides Since 1997

Expert Opinion on Investigational Drugs, 1999
André Bryskier, A Bryskier
exaly  

Ketolides

2016
openaire   +1 more source

Structures of Ketolides and Macrolides Determine Their Mode of Interaction With the Ribosomal Target Site

Journal of Antimicrobial Chemotherapy, 2001
Stephen Douthwaite, W Scott Champney
exaly  

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