Clinical Nutritional Study of Minimum Protein and Caloric Requirements for Man. Annual Report, Sep. 1965 - Sep. 1966 [PDF]
, 1966 Minimum protein and caloric requirements for prolonged manned spaceflight and space ...
Calloway, D. H., Margen, S.
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Ketone Bodies as a Therapeutic for Alzheimer's Disease [PDF]
Neurotherapeutics, 2008 An early feature of Alzheimer's disease (AD) is region-specific declines in brain glucose metabolism. Unlike other tissues in the body, the brain does not efficiently metabolize fats; hence the adult human brain relies almost exclusively on glucose as an energy substrate.
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Frontiers in Cellular NeuroscienceThe ketogenic diet increases ketone bodies (β-hydroxybutyrate and acetoacetate) in the brain, and ameliorates epileptic seizures in vivo. However, ketone bodies exert weak or no effects on electrical activity in rodent hippocampal slices.
Hao Wen, Nagisa Sada, Tsuyoshi Inoue
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STUDIES ON DIABETES MELLITUS: THE RELATION OF STRESSFUL LIFE SITUATIONS TO THE CONCENTRATION OF KETONE BODIES IN THE BLOOD OF DIABETIC AND NON-DIABETIC HUMANS 1 [PDF]
, 1950 Lawrence E. Hinkle +4 more
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Diabetic Ketoacidosis: Pathophysiology and Treatment [PDF]
, 2015 The pathophysiology of DKA in patients with T1D is addressed, followed by a discussion of proper emergency treatment for this life-threatening ...
Mumme, Laura E.
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Diabetes, obesity and metabolism, 2018 Sodium glucose co‐transporter 2 (SGLT2) inhibitors have been associated with increased serum ketone body levels in patients with type 2 diabetes mellitus (T2DM).
D. Polidori +5 more
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Ketone body metabolism and cardiovascular disease
American Journal of Physiology-Heart and Circulatory Physiology, 2013 Ketone bodies are metabolized through evolutionarily conserved pathways that support bioenergetic homeostasis, particularly in brain, heart, and skeletal muscle when carbohydrates are in short supply. The metabolism of ketone bodies interfaces with the tricarboxylic acid cycle, β-oxidation of fatty acids, de novo lipogenesis, sterol biosynthesis ...
David G. Cotter +2 more
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The Effect of Ketogenic Diet Treatment in Drug-resistant Epilepsies of Childhood
Türk Nöroloji Dergisi, 2018 Epilepsy is an important health issue. The interest in ketogenic diet (KD) treatment in children and adolescents with drug-resistant epilepsy has increased in recent years.
Gizem Özata Uyar, Nevin Şanlıer
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Therapeutic Potential of Ketone Bodies for Patients With Cardiovascular Disease: JACC Focus Seminar.
Journal of the American College of Cardiology, 2021 Salva R. Yurista +5 more
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Use of ketone bodies as energy substrates at different developmental stages and under different oxygen tensions by in vitro-produced bovine embryos [PDF]
, 2011 In vitro-produced bovine embryos can develop into hatched blastocysts in the presence of acetoacetate and b-hydroxybutyrate, which may be derived from lipid breakdown.
Díez, Carmen, Gómez, Enrique
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