Results 61 to 70 of about 4,666,601 (266)

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]

, 2015
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M, Casas, J-P, Chaturvedi, N, Fatemifar, G, Hingorani, AD, Hughes, AD, Jarvelin, M-R, Kahonen, M, Kangas, AJ, Kettunen, J, Kivimaki, M, Lawlor, DA, Lehtimaki, T, Mantyselka, P, Perola, M, Raitakari, OT, Salomaa, V, Sattar, N, Smith, GD, Soininen, P, Tiainen, M, Tillin, T, Tynkkynen, T, Vanhala, M, Wang, Q, Wurtz, P   +25 more
core   +2 more sources

Characteristics of Cardiac Ketone Body Metabolism Throughout the Life Cycle

Cardiovascular Therapeutics
Ketone bodies can serve as energy substrates for the heart and perform important molecular signal transduction functions. In recent years, the therapeutic potential of ketone bodies has become a research hotspot in the field of cardiovascular diseases ...
Lei Li, Xiaojian Song, Xiurui Ma, Yanwu Xu   +3 more
doaj   +1 more source

Relationships between milk ketone bodies and selected milk indicators during conventional and extended lactation [PDF]

Journal of Central European Agriculture
During lactation, dairy cows undergo various metabolic changes that are reflected not only in milk yield but also in milk composition. This study aimed to determine the milk performance and composition depending on the stage of lactation and describe ...
Karolína REINDL, Lucie HASOŇOVÁ, Roman KONEČNÝ, Michaela HORČIČKOVÁ, Jan TRÁVNÍČEK, Natalia CLIMOVA, Simona JANOUŠEK HONESOVÁ, Martin KVÁČ, Jindřich ČÍTEK, Oto HANUŠ, Eva SAMKOVÁ   +10 more
doaj   +1 more source

Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]

, 2016
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E., Capani, Francisco, Castilla Lozano, Maria del Rocio, Holubiec, Mariana Ines, Logica Tornatore, Tamara Maite Ayelén, Riviere, Stephanie   +5 more
core   +1 more source

Ketone Body Infusion With 3‐Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background High levels of ketone bodies are associated with improved survival as observed with regular exercise, caloric restriction, and—most recently—treatment with sodium–glucose linked transporter 2 inhibitor antidiabetic drugs.
Lars C. Gormsen, Mads Svart, Henrik Holm Thomsen, Esben Søndergaard, Mikkel H. Vendelbo, Nana Christensen, Lars Poulsen Tolbod, Hendrik Johannes Harms, Roni Nielsen, Henrik Wiggers, Niels Jessen, Jakob Hansen, Hans Erik Bøtker, Niels Møller   +13 more
doaj   +1 more source

Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I [PDF]

, 2007
Glutaric acidemia type I (GA-I) is an inherited disorder of lysine and tryptophan metabolism presenting with striatal lesions anatomically and symptomatically similar to Huntington disease.
Banos, Blemings, Cathy Housman, Colon, Cornford, Daniel, Daniel, Hayashi, Ian Simpson, James P. O’Callaghan, James R. Connor, Jelena Lazovic, Juliet, Kathryn LaNoue, Keith C. Cheng, Kyllerman, Leibel, Lowry, Michael Woontner, Miller, Provencher, Rao, Russell, Russell E. Jacobs, Stephen I. Goodman, Strauss, Strauss, Tews, Vonsattel, William J. Zinnanti, Williamson   +30 more
core   +3 more sources

Ketonemia variability through menstrual cycle in patients undergoing classic ketogenic diet

Frontiers in Nutrition, 2023
IntroductionKetogenic dietary therapies (KDT) are well-established, safe, non-pharmacologic treatments used for children and adults with drug-resistant epilepsy and other neurological disorders.
Ludovica Pasca, Ludovica Pasca, Cinzia Ferraris, Cinzia Ferraris, Monica Guglielmetti, Monica Guglielmetti, Costanza Varesio, Costanza Varesio, Martina Totaro, Martina Totaro, Claudia Trentani, Claudia Trentani, Claudia Marazzi, Claudia Marazzi, Ilaria Brambilla, Elena Ballante, Elena Ballante, Marisa Armeno, Gabriela Reyes Valenzuela, Roberto H. Caraballo, Pierangelo Veggiotti, Anna Tagliabue, Anna Tagliabue, Valentina De Giorgis, Valentina De Giorgis   +24 more
doaj   +1 more source

Effect of aerobic effort on some kidneys functions of cyclists [PDF]

مجلة الرافدين للعلوم الرياضية, 2009
The effect of aerobic effort on some kidneys functions of cyclists was studies on(5) Ninava champions cyclists (18.8 3.49 yrs ,682.29 kg, 1.75  4.20m).The procedures include pre and post aerobic effort Measurement of white blood cells(WBC), proteins ...
Wasan S.Rashid, Nashwan I.Abdullah
doaj   +1 more source

The Effect of the Ketogenic Diet on the Therapy of Neurodegenerative Diseases and Its Impact on Improving Cognitive Functions

Dementia and Geriatric Cognitive Disorders Extra, 2022
The ketogenic diet (KD) is a high-fat and low-carbohydrate diet with controlled amounts of protein. The use of drastic caloric restriction or ultralow-carbohydrate diets increases the production of ketone bodies, which are an alternative energy substrate
Klaudia Grochowska, Anna Przeliorz
doaj   +1 more source

The effect of ketone bodies on renal ammoniogenesis [PDF]

Journal of Clinical Investigation, 1971
Infusion of ketone bodies to ammonium chloride-loaded acidotic dogs was found to induce significant reduction in urinary excretion of ammonia. This effect could not be attributed to urinary pH variations. Total ammonia production by the left kidney was measured in 25 animals infused during 90 min with the sodium salt of D,L-beta-hydroxybutyric acid ...
Patrick Vinay, Pierre Martin, Yolande Lussier, Gérard E. Plante, Pierre Robitaille, Guy Lemieux   +5 more
openaire   +2 more sources