Results 61 to 70 of about 29,891 (282)
The depolarizing action of GABA in cultured hippocampal neurons is not due to the absence of ketone bodies. [PDF]
PLoS ONE, 2011 Two recent reports propose that the depolarizing action of GABA in the immature brain is an artifact of in vitro preparations in which glucose is the only energy source. The authors argue that this does not mimic the physiological environment because the
Jaylyn Waddell +3 more
doaj +1 more source
Ketone Bodies as Anti-Seizure Agents [PDF]
Neurochemical Research, 2017 There is growing evidence that ketone bodies (KB)-derived from fatty acid oxidation and produced during fasting or consumption of high-fat diets-can exert broad neuroprotective effects. With respect to epilepsy, KB (such as β-hydroxybutyrate or BHB, acetoacetate and acetone) have been shown to block acutely induced and spontaneous recurrent seizures in
Simeone, Timothy A +2 more
openaire +4 more sources
Advanced Materials Technologies, EarlyView.This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias +4 more
wiley +1 more source
Ketone body, as an emerging modulator of metabolic reprogramming and epigenetics in breast cancer [PDF]
Iranian Journal of Basic Medical SciencesThe metabolic profile of cancer cells, notably their reliance on glucose as a primary energy source for proliferation, sets them apart from normal cells. This metabolic dependency may significantly affect their invasive potential when an adequate glucose
Fatemeh Mehdikhani +4 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Metabolic Effects of the Very-Low-Carbohydrate Diets: Misunderstood "Villains" of Human Metabolism
Journal of the International Society of Sports Nutrition, 2004 During very low carbohydrate intake, the regulated and controlled production of ketone bodies causes a harmless physiological state known as dietary ketosis. Ketone bodies flow from the liver to extra-hepatic tissues (e.g., brain) for use as a fuel; this
Manninen Anssi H
doaj +1 more source
The ketone body β-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast cell function [PDF]
, 2022 Christina Li‐Ping Thio +4 more
openalex +1 more source
Advanced Robotics Research, EarlyView.Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen +3 more
wiley +1 more source
Multi‐Material Additive Manufacturing of Soft Robotic Systems: A Comprehensive Review
Advanced Robotics Research, EarlyView.This review explores the transformative role of multi‐material additive manufacturing (MMAM) in the development of soft robotic systems. It presents current techniques, materials, and design strategies that enable functionally graded and adaptive structures.
Ritik Raj +2 more
wiley +1 more source
Myocardial Ischemia Suppresses Ketone Body Utilization
Journal of the American College of Cardiology, 2019 Ketone bodies (acetoacetate, acetone, and β-hydroxybutyrate [βOHB]) are metabolites that are well known as alternative energy sources [(1)][1]. Recent studies have reported that sodium glucose cotransporter-2 (SGLT2) inhibitors increased ketone body concentrations along with a significant ...
Yuichiro, Arima +9 more
openaire +2 more sources