Results 171 to 180 of about 205,384 (273)

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Donor–Acceptor Pentacene Analogues With Near‐Infrared Emission and Tunable Aromaticity

Angewandte Chemie, EarlyView.
Air‐ and photostable heterocyclic pentacene analogues with donor and acceptor groups flanking a para‐quinodimethane core exhibit large dipole moments, narrow bandgaps, reversible redox behavior, and NIR‐I to NIR‐II absorption and emission with pronounced solvatochromism.
Krzysztof Nowak, Olaf Morawski, Muhammad Yasir Mehboob, Maja Morawiak, Krzysztof Noworyta, Cina Foroutan‐Nejad, Marek Grzybowski   +6 more
wiley   +2 more sources

Cooperative NHC and Photoredox Dual Catalysis for the Construction of Carbonyl Compounds. [PDF]

ACS Omega
Dhayalan V.
europepmc   +1 more source

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Annals of Neurology, EarlyView.
Objective Lactate is increasingly recognized as an energy substrate, but its relevance to amyotrophic lateral sclerosis (ALS) remains unclear. We examined whether blood lactate is associated with survival and weight loss in ALS. Methods This retrospective study included an Australian exploratory cohort and a Japanese validation cohort with clinical ...
Ryutaro Nakamura, Frederik J. Steyn, Shuhei Kobashi, Nobuhiro Ogawa, Akihiro Kitamura, Isamu Yamakawa, Robert D. Henderson, Shyuan T. Ngo, Makoto Urushitani   +8 more
wiley   +1 more source

Speciation, Structural Refinement, and Distribution of Ti Sites in Titanium Silicalite‐1 From 47/49Ti NMR Crystallography at 28.2 Tesla

Angewandte Chemie, EarlyView.
Titanium silicalite‐1 (TS‐1), used in industrial selective oxidation processes, depends on specific, yet still unresolved Ti sites, dispersed within the framework of an MFI‐zeolite. Applying high field (28.2 T) 47/49Ti NMR and 17O NMR spectroscopy for an array of TS‐1 catalysts enables the development of an NMR crystallography protocol and the ...
Christoph J. Kaul, Jonas Koppe, Lukas Lätsch, Michael Wörle, Sadig Aghazada, Jacob B. Holmes, Christina Wartmann, Mingji Zheng, Albrecht Berkessel, Trees De Baerdemaeker, Andrei‐Nicolae Parvulescu, Karsten Seidel, J. Henrique Teles, Alexander V. Yakimov, Christophe Copéret   +14 more
wiley   +2 more sources

One‐Dimensional Polycyclic Aromatic Hydrocarbons Incorporating Multiple Dithiafulvene Units—Novel Multi‐Redox and Electrochromic Systems

Angewandte Chemie, EarlyView.
Planar polycyclic aromatic hydrocarbons (PAHs) incorporating three or four dithiafulvene (DTF) units were synthesized via Horner–Wadsworth–Emmons reactions to create large π‐conjugated redox‐active frameworks. These molecules display strong intermolecular associations and distinct odd–even redox behavior, enabling formation of mixed‐valence and radical‐
Cecilie Rindom, Florim Seljmani, Lukas Bradley Woodcock, Mogens Brøndsted Nielsen   +3 more
wiley   +2 more sources

Neuronal metabolism role in ketogenic diet improvements in bortezomib-induced painful peripheral neuropathy mouse model. [PDF]

Pain Rep
Heslop LL, Madden TK, Totta-Griese G, Crowards SJ, Hauser W, Ryals J, Baumbauer KM, Wilkins HM, Wright DE.   +8 more
europepmc   +1 more source

Alkoxysulfonium Salts Unlock Access to New Aryl Sulfonium Salts for Cross‐Coupling

Angewandte Chemie, EarlyView.
Hard‐to‐access (hetero)aryl sulfonium salts are prepared using stable methoxysulfonium salts in combination with the magnesiation of (hetero)aryl bromides. The approach allows access to aryl sulfonium salts bearing electron‐deficient (hetero)aryl rings, or electron‐rich aryl motifs in which the sulfonium motif resides at an alternative position on the ...
Rachel E. Brown, Navpreet Kaur, Anne‐Chloe M. A. Nassoy, Ciro Romano, David J. Procter   +4 more
wiley   +2 more sources

Stereospecific Transition-Metal-Free Alkylation of Chiral Non-Racemic Secondary Tosylates with Cyanohydrins: Convenient Access to Enantiomerically Enriched α-Tertiary Ketones. [PDF]

Angew Chem Int Ed Engl
Ma J, Li H, Majhi J, Evans PA.
europepmc   +1 more source

Chemical Upcycling of Nitrile Butadiene Rubbers to Polyamines and Polyols by Chemoselective Catalytic Hydrogenation

Angewandte Chemie, EarlyView.
We demonstrate here the transformation of NBR (Nitrile butadiene rubber) including post‐consumer waste sourced from nitrile gloves and o‐rings into polyamines and polyols via ruthenium catalyzed hydrogenation. ABSTRACT We report here two new approaches for the chemical recycling/upcycling of nitrile butadiene rubber (NBR) to make either polyamines or ...
Alejandra Sophia Lozano Perez, Raymundo Marcial‐Hernandez, Harini Sampathkumar, Oluchi Emenike, Ketan Pancholi, Claire N. Brodie, Daniel M. Dawson, Amit Kumar   +7 more
wiley   +2 more sources