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NiH‐Catalyzed Enantioconvergent α‐Alkenylation of Carbonyl Compounds via Markovnikov Alkyne Hydronickellation

open access: yesAngewandte Chemie, EarlyView.
A NiH‐catalyzed α‐alkenylation via Markovnikov hydronickellation of alkynes enables convenient access to α‐chrial β‐methylene carbonyl frameworks that are prevalent in biorelevant molecules. High regio‐ and enantioselectivities have been achieved with excellent functional group tolerance and applicability toward complex structures. The β‐methylene unit
Hyeontaek Nam   +3 more
wiley   +2 more sources

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