Results 11 to 20 of about 23,218 (270)
Proprotein Convertase Subtilisin Kexin 9 Inhibitors [PDF]
Cardiology Clinics, 2018 High levels of low-density lipoprotein cholesterol (LDL-C) are directly associated with an increased risk of cardiovascular disease. Reducing LDL-C levels reduces the incidence of cardiovascular events. Several lipid-lowering approaches are available to achieve the LDL-C levels recommended by current guidelines, statins being the first-line therapy ...
A. Pirillo, A. L. Catapano
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Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors [PDF]
Canadian Medical Association Journal, 2019 PCSK9 is a protease that degrades hepatic LDL-C receptors. Evolocumab and alirocumab are fully human monoclonal antibodies administered as subcutaneous injections that inhibit PCSK9, preserving receptor availability to clear circulating LDL-C.[1][1],[2][2] In randomized, placebo-controlled ...
Derek, Leong, Peter E, Wu
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Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
PCSK5 (Proprotein Convertase Subtilisin/Kexin Type 5) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2015 Review on PCSK5 (Proprotein Convertase Subtilisin/Kexin Type 5), with data on DNA, on the protein encoded, and where the gene is implicated.
Khatib, M, Demoures, B
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PCSK1 (proprotein convertase subtilisin/kexin type 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018 PCSK1 is a serine protease involved in the proteolytic processing of a variety of protein precursors mainly neuropeptides and prohormones. In 1991, PC1/3; also known as PCSK1, PC1, PC3, and SPC3 was identified at the same time by two laboratories separately. The human and mouse PCSK1 genes are localized on chromosomes 5 and 13, respectively.
Demoures, Béatrice +2 more
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Repetitive DNA is Functional and Encodes Parts of the Non‐Coding RNA Repertoire
Advanced Genetics, 2022 This is a commentary on the article by Eviatar Nevo and Kexin Li entitled “Sympatric Speciation in Mole Rats and Wild Barley and Their Genome Repeatome Evolution: A Commentary”, published recently in Advanced Genetics.
James A. Shapiro
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: The inflammatory response in the tumor immune microenvironment has implications for the progression and prognosis in glioma. However, few inflammatory response-related biomarkers for lower-grade glioma (LGG) prognosis and immune infiltration ...
Yudong Cao +8 more
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Exploring the Changing Pathway to Cultivating an Elite ‘International’ Child in China [PDF]
SHS Web of Conferences, 2023 In the context of globalization, upper-middle-class parents choose international schools as an educational strategy to prepare their children to become cosmopolitans through the accumulation of linguistic and cosmopolitan cultural capital that can be ...
Ma Kexin
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The Impact of Parenting style on the Psychological Resilience of Adolescents [PDF]
SHS Web of ConferencesThe mental health of adolescents is a hot topic of discussion in today's society. Researchers have found that family environment and atmosphere have an impact on the emotional, cognitive, and behavioral development of adolescents.
Feng Jiayi +3 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2019 Infection with the opportunistic fungal pathogen, Pneumocystis jirovecii causes life-threatening pneumonia in immunocompromised individuals. In addition to HIV-1 infected patients, individuals at risk of Pneumocystis infection include those receiving ...
Viviana Cobos Jiménez +3 more
doaj +1 more source