Results 121 to 130 of about 2,783,643 (311)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Sleep Period Optimization Model For Layered Video Service Delivery Over eMBMS Networks

, 2015
Long Term Evolution-Advanced (LTE-A) and the evolved Multimedia Broadcast Multicast System (eMBMS) are the most promising technologies for the delivery of highly bandwidth demanding applications.
Carlà, Lorenzo, Chiti, Francesco, Fantacci, Romano, Tassi, Andrea   +3 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

In vivo fluorescence imaging of nanocarriers in near-infrared window II based on aggregation-caused quenching

Journal of Nanobiotechnology
Accurate fluorescence imaging of nanocarriers in vivo remains a challenge owing to interference derived mainly from biological tissues and free probes. To address both issues, the current study explored fluorophores in the near-infrared (NIR)-II window ...
Zichen Zhang, Chang Liu, Yi Lu, Weili Zhao, Quangang Zhu, Haisheng He, Zhongjian Chen, Wei Wu   +7 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Preparation of a benziodazole-type iodine(III) compound and its application as a nitrating reagent for synthesis of furazans via a copper-catalyzed cascade process

Communications Chemistry
The existing hypervalent I(III) reagents bearing ONO2 group are limited in types and their applications primarily focused on the nitrooxylation reactions featuring a fully-exo fashion. Herein, a benziodazole-type O2NO-I(III) compound was prepared and its
Zhifang Yang, Jun Xu, Yuli Sun, Xuemin Li, Bohan Jia, Yunfei Du   +5 more
doaj   +1 more source

High intensity forced ultrasound-driven ferroptosis as a strategy for anti-tumor immune priming

Acta Pharmaceutica Sinica B
Cold tumors have a poor response to tumor immunotherapy due to low immune cell infiltration and the ability to evade immune attacks. Converting cold tumors into hot tumors can enhance the clinical effectiveness of anti-tumor immunotherapy. High-intensity
Xuejing Li, Jiayi Wu, Ruizhe Xu, Xifeng Qin, Siyu Wang, Wuli Yang, Zhiqing Pang   +6 more
doaj   +1 more source

The Impact of Cognitive versus Affective Aspects on Consumer Usage of Financial Service Delivery Channels [PDF]

This paper explores the consumer decision-making process when using service delivery channels. Among service delivery channels, the main focus of the research concerns technology-based delivery channels.
Ana S. Branca
core  

Fair Task Allocation in Crowdsourced Delivery

, 2018
Faster and more cost-efficient, crowdsourced delivery is needed to meet the growing customer demands of many industries, including online shopping, on-demand local delivery, and on-demand transportation.
Basik, Fuat, Ferhatosmanoglu, Hakan, Gedik, Bugra, Wu, Kun-Lung   +3 more
core   +2 more sources