Results 131 to 140 of about 7,763,303 (316)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Commonwealth Bank Building, Brisbane Street, Launceston [picture] /
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892262 ...
Key, Mike, 1951-
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Old Toll House, Rocks Road on Derwent River, New Norfolk [picture].
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892270 ...
Key, Mike, 1951-
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
St Peter's Catholic Church. Hillside Crescent, New Norfolk [picture].
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892270 ...
Key, Mike, 1951-
core
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Hunters Hotel, Orr Street, Queenstown. Built late 1800s [picture].
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892265 ...
Key, Mike, 1951-
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Sand football ground off Batchelor Street, Queenstown [picture].
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892265 ...
Key, Mike, 1951-
core