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Key issues in non-viral gene delivery

Advanced Drug Delivery Reviews, 1998
The future of non-viral gene therapy depends on a detailed understanding of the barriers to delivery of polynucleotides. These include physicomechanical barriers, which limit the design of delivery devices, physicochemical barriers that influence self-assembly of colloidal particulate formulations, and biological barriers that compromise delivery of ...
C W, Pouton, L W, Seymour
openaire   +3 more sources

Key Concepts in Healthcare Delivery

2017
This chapter examines several key concepts in healthcare within an African context. The concepts include health, access to health, UHC and health systems. This chapter starts with the concept of “health,” the definition of which has been a recent subject of contention.
Jimoh Amzat, Oliver Razum
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Drug Delivery is Key to Treatment

Eureka!, 2020
A prototype polymer patch capable of performing the same role as actual heart tissue could be a gamechanger.
openaire   +1 more source

Drug delivery to mitochondria: the key to mitochondrial medicine

Advanced Drug Delivery Reviews, 2000
The major function of mitochondria in human cells is to provide ATP by oxidative phosphorylation. However, mitochondria have many other roles including the modulation of intracellular calcium concentration and the regulation of apoptotic cell death.
M P, Murphy, R A, Smith
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Overview of Quantum Key Distribution Network Key-Delivery Specifications

2025 International Conference on Quantum Communications, Networking, and Computing (QCNC)
Quantum Key Distribution (QKD), a secret key agreement primitive, makes possible long-awaited real-world Information-Theoretical Security (ITS). In the last twenty years, the development of QKD-based networks that deliver ITS keys to distant parties has been a focus of the academic and industry sectors.
Mehic M.   +5 more
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Key to Delivery: The (Epi-)genome Editing Vector Toolbox

2018
Curing a genetic disease by repairing the underlying genetic defect is a fascinating concept that has been addressed so far by gene compensation therapy. For this, a functional copy of the gene in question together with elements controlling its expression is produced as a vector and introduced ex vivo into the patient's own cells that subsequently are ...
Sabrina, Just, Hildegard, Büning
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