Results 51 to 60 of about 2,764,347 (308)
Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]
, 2019 "Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A +11 more
core
Teledentistry: An Innovative Workforce Model for Dental Hygienists [PDF]
, 2020 Objective/Aims: This review of literature seeks to explore teledentistry as an alternative dental hygiene workforce model that places a dental hygienist in the role of the mid-level practitioner as part of a digitally-connected oral healthcare team.
Khau, Kayla T., Nguyen, Hannah H.
core +1 more source
Authentic professional development: Key to quality service delivery
South African Actuarial Journal, 2015 The Actuarial Society of South Africa (‘Actuarial Society’) requires its members to honour their professional promise to deliver specialist and up-to-date actuarial expertise that is ethical and subject to professional oversight. The purpose of this study is to investigate how the ActuarialSociety can encourage its members to develop and maintain the ...
Lowther, Michael, McMillan, Wendy
openaire +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
BMC MedicineBackground Prediabetes refers to the transitional stage from normal glucose metabolism to diabetes. The International Diabetes Federation guidelines reported that, as of 2024, approximately 1.12 billion people globally were in the prediabetes stage ...
Yike Wu +19 more
doaj +1 more source
Working Report #1: Service Model Accessibility (Service Provider Perspectives) [PDF]
, 2009 This report examines the differences in service accessibility across central, integrated, and school/community based child welfare service delivery models including geographic proximity to families, acceptability of the setting to families, and ...
Cameron, Gary, Hazineh, Lirondel
core +1 more source
AAVR-Displaying Interfaces: Serotype-Independent Adeno-Associated Virus Capture and Local Delivery Systems. [PDF]
, 2019 Interfacing gene delivery vehicles with biomaterials has the potential to play a key role in diversifying gene transfer capabilities, including localized, patterned, and controlled delivery. However, strategies for modifying biomaterials to interact with
Cho, Mira +5 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source