Lock cohorting: A general technique for designing NUMA locks [PDF]
Multicore machines are quickly shifting to NUMA and CC-NUMA architectures, making scalable NUMA-aware locking algorithms, ones that take into account the machines' non-uniform memory and caching hierarchy, ever more important.
Dice, David +2 more
core +2 more sources
Silences in the boom: coal seam gas, neoliberalizing discourse, and the future of regional Australia
In high-stakes resource use struggles currently playing out across the world, different beliefs about economics and "growth-first" regional development underpin decisions and dynamics that have far-reaching consequences.
Alexandra Mercer +2 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Highly coherent phase-lock of an 8.1 μm quantum cascade laser to a turn-key mid-IR frequency comb [PDF]
B. Chomet +7 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Health Care Coverage: Job Lock and the Potential Impact of the Patient Protection and Affordable Care Act [PDF]
[Excerpt] The majority of Americans—about 55 percent in 2010—rely on employer-sponsored health care coverage, which is largely subsidized by most employers and thus less costly to employees than coverage purchased by individuals on their own.
United States Government Accountability Office
core +2 more sources
The Lock-free $k$-LSM Relaxed Priority Queue
Priority queues are data structures which store keys in an ordered fashion to allow efficient access to the minimal (maximal) key. Priority queues are essential for many applications, e.g., Dijkstra's single-source shortest path algorithm, branch-and ...
Gruber, Jakob +3 more
core +2 more sources
Lessons from Love-Locks: The archaeology of a contemporary assemblage [PDF]
This document is the Accepted Manuscript version. The final, definitive version of this paper has been published in Journal of Material Culture, November 2017, published by SAGE Publishing, All rights reserved.Loss of context is a challenge, if not the ...
Bord J +31 more
core +2 more sources
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source

