Results 51 to 60 of about 6,638,555 (335)

Colloids with key-lock interactions: non-exponential relaxation, aging and anomalous diffusion

, 2007
The dynamics of particles interacting by key-lock binding of attached biomolecules are studied theoretically. Experimental realizations of such systems include colloids grafted with complementary single-stranded DNA (ssDNA), and particles grafted with ...
Alexei V. Tkachenko, D. Stauffer, J.-P. Bouchaud, Nicholas A. Licata   +3 more
core   +1 more source

Quantum-classical correspondence in circularly polarized high harmonic generation [PDF]

, 2013
Using numerical simulations, we show that atomic high order harmonic generation, HHG, with a circularly polarized laser field offers an ideal framework for quantum-classical correspondence in strong field physics.
Bandrauk, A. D., Chandre, Cristel, Kamor, Adam, Mauger, Francois, Uzer, Turgay   +4 more
core   +4 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

“Lock ‘Em Up . . .” but Where’s the Key? Transformative Drama with Incarcerated Youth

Journal of Contemporary Issues in Education, 2014
A research study doing applied theatre with youth at an Alberta, Canada young offender facility, asks: How can participatory drama contribute to the education of incarcerated youth to avoid future negative outcomes of their “at-risk” behaviours?
Diane Conrad
doaj   +1 more source

A comparison between internal protein nanoenvironments of α-helices and β-sheets.

PLoS ONE, 2020
Secondary structure elements are generally found in almost all protein structures revealed so far. In general, there are more β-sheets than α helices found inside the protein structures.
Ivan Mazoni, Jose Augusto Salim, Fabio Rogerio de Moraes, Luiz Borro, Goran Neshich   +4 more
doaj   +1 more source

Entropic torque

, 2002
Quantitative predictions are presented of a depletion-induced torque and force acting on a single colloidal hard rod immersed in a solvent of hard spheres close to a planar hard wall. This torque and force, which are entirely of entropic origin, may play
A. Vrij, B. Götzelmann, D. Andrienko, K. R. Mecke, M. Dijkstra, M. Kinoshita, R. Dickman, R. Evans, R. Roth, R. van Roij, R. J. Ellis, S. Asakura, S. Asakura, S. Dietrich, T. Biben, Y. Rosenfeld, Y. Rosenfeld   +16 more
core   +2 more sources

Key-lock pair mechanism for access control using tribes of Farey fractions. [PDF]

, 2000
We propose a new single key-lock mechanism based on the concept of an access control matrix. In this system, each file is given a lock and each user is given a key and through simple operations on keys and locks the user access privilege can be revealed.
Chandrashekhar, H., Nagaraj, M.
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Um paradigma da química medicinal: a flexibilidade dos ligantes e receptores A medicinal chemistry paradigm: ligands and receptor flexibility

Química Nova, 2005
In general, molecular modeling techniques applied in medicinal chemistry have been static and drug based. However the active site geometry and the intrinsic flexibility of both receptor and ligand are fundamental properties for molecular recognition and ...
Hugo Verli, Eliezer J. Barreiro
doaj   +1 more source

Exploring cysteine regulation in cancer cell survival with a highly specific “Lock and Key” fluorescent probe for cysteine† †Electronic supplementary information (ESI) available: Synthesis, experimental procedures, supplemental spectra and imaging data, and 1H-, 13C-NMR, and MS spectra. See DOI: 10.

Chemical Science, 2019
Using a highly specific “lock and key” fluorescent Cys probe, we confirmed that targeting Cys metabolism to deplete intracellular Cys is a more potent strategy to sensitize cancer cells to chemotherapies.
Jing Liu, Mengxing Liu, Hongxing Zhang, Xuehong Wei, Juan-juan Wang, M. Xian, Wei Guo   +6 more
semanticscholar   +1 more source