Results 91 to 100 of about 1,025,886 (293)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

State of the states: April 2015 state and territory economic performance report [PDF]

open access: yes
Overview: How are Australia\u27s states and territories performing? Each quarter CommSec assesses the overall economic performance of each jurisdiction on eight key indicators: economic growth; retail spending; equipment investment; unemployment ...
CommSec
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Identifying and ranking key factors affecting the provision of financial services

open access: yesحسابداری و شفافیت مالی
Purpose: The main objective of this research is to present a conceptual model for identifying and ranking key factors affecting financial services.
Reza Shamgani   +1 more
doaj  

Ranking of key factors in agility strategy, reconstruction and optimization of equipment by DEMATEL method [PDF]

open access: yesعلوم و فنون نظامی, 2017
Speed, agility, mobility, saving, dispersion, security, accuracy and flexibility are one of the most important features of future wars. Given the sanctions imposed on our country in the field of military equipment, it is essential to have an agile ...
kiyanoush bahrami   +1 more
doaj  

Simple Key Enumeration (and Rank Estimation) Using Histograms: An Integrated Approach

open access: yes, 2016
The main contribution of this paper, is a new key enumeration algorithm that combines the conceptual simplicity of the rank estimation algorithm of Glowacz et al. (from FSE 2015) and the parallelizability of the enumeration algorithm of Bogdanov et al. (SAC 2015) and Martin et al. (from ASIACRYPT 2015). Our new algorithm is based on histograms.
Poussier, Romain   +3 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Birth Satisfaction Units (BSU): Measuring Cross-National Differences in Human Well-Being [PDF]

open access: yes
While everyone agrees that GDP per capita is an inadequate measure of a country’s overall “development” it is difficult to specify what, if anything, should take its place as a useful single summary number (or even just ranking).
Lant Pritchett
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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