Results 91 to 100 of about 239,474 (338)

The importance of Ki-67 proliferation index in small cell lung cancer

The Egyptian Journal of Bronchology
Background As in numerous cancers, the connection between the Ki-67 proliferation index and response to treatment in cellular breakdown in the lungs is underlined.
Seda Beyhan Sağmen, Coşkun Doğan, Sevda Cömert, Nesrin Kıral, Elif Torun Parmaksız, Ali Fidan, Nagehan Ozdemir Barisik, Sule Karabulut Gul   +7 more
doaj   +1 more source

Variability of the Ki-67 proliferation index in gastroenteropancreatic neuroendocrine neoplasms - a single-center retrospective study

BMC Endocrine Disorders, 2018
Background The Ki-67 index in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) may change throughout the disease course. However, the definitive effect of Ki-67 variability on GEP-NENs remains unknown.
Huiying Shi, Qin Zhang, Chaoqun Han, Ding Zhen, Rong Lin   +4 more
doaj   +1 more source

Micro Regional Heterogeneity of ⁶⁴Cu-ATSM and ¹⁸F-FDG Uptake in Canine Soft Tissue Sarcomas: Relation to Cell Proliferation, Hypoxia and Glycolysis [PDF]

, 2015
Tumour microenvironment heterogeneity is believed to play a key role in cancer progression and therapy resistance. However, little is known about micro regional distribution of hypoxia, glycolysis and proliferation in spontaneous solid tumours.
Clemmensen, Andreas E., El Ali, Henrik H., Hansen, Anders Elias, Kjær, Andreas, Kristensen, Annemarie T, Oxboel, Jytte, Zornhagen, Kamilla Westarp   +6 more
core   +4 more sources

Electrically Tunable On‐Chip Topological Photonics with Integrated Carbon Nanotubes

Advanced Functional Materials, EarlyView.
This work demonstrates electrically tunable on‐chip topological THz devices by integrating 2D carbon nanotube (CNT) sheets with valley‐Hall photonic crystals, enabling broadband transmission modulation (71% modulation depth) and tunable narrowband filtering (0.54 GHz shift) through electrically induced thermal tuning. This advancement paves the way for
Jifan Yin, Wenhao Wang, Thomas Caiwei Tan, Abhishek Kumar, Ridong Jia, Nikhil Navaratna, Ranjan Singh, Lijuan Xie   +7 more
wiley   +1 more source

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Role of Ki-67 in the Grading of Mucoepidermoid Carcinomas

Journal of Rawalpindi Medical College, 2015
Background: To determine the expression of Ki-67 in mucoepidermoid carcinoma (MEC) and to correlate with histological grades. Methods: In this descriptive study, histopathological grading of mucoepidermoid carcinomas was done on the basis of grading ...
Sobia Siddique
doaj  

Cutaneous Canine Mast Cell Tumor: The Use of Proliferative Markers (Ki-67 and Ki-67 × AgNOR) in Cytological Samples for Diagnosis and Prognosis

Veterinary Sciences
A cytological grading system for canine mast cell tumors (MCTs) has been developed, but its integration into clinical routine has been hindered due to its diagnostic limitations.
Christina Marouda, Tilemahos Anagnostou, Barbara Brunetti, Ioannis Savvas, Lysimachos G. Papazoglou, Dimitra Psalla   +5 more
doaj   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

Predictive Value of Tumor Ki-67 Expression in Two Randomized Trials of Adjuvant Chemoendocrine Therapy for Node-Negative Breast Cancer [PDF]

, 2017
Several small studies have reported that having a high percentage of breast tumor cells that express the proliferation antigen Ki-67 (ie, a high Ki-67 labeling index) predicts better response to neoadjuvant chemotherapy.
Brown, R. W., Castiglione-Gertsch, Monica, Coates, Alan S., Colleoni, Marco, Gelber, Richard D., Goldhirsch, Aron, Golouh, Rastko, Gusterson, Barry A., Kovács, Anikó, Maffini, Fausto, Maiorano, Eugenio, Mastropasqua, Mauro G., Perin, Tiziana, Pillay, Komala, Price, Karen N., Regan, Meredith M., Viale, Giuseppe, Öhlschlegel, Christian   +17 more
core  

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source