Results 11 to 20 of about 239,474 (338)
The intrinsically disorderly story of Ki-67 [PDF]
Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review some of the current literature regarding the protein.
Lucy Remnant +4 more
doaj +4 more sources
AbstractKi-67 serves as a prominent cancer marker. We describe how expression of the MKI67 gene coding for Ki-67 is controlled during the cell cycle. MKI67 mRNA and Ki-67 protein are maximally expressed in G2 phase and mitosis. Expression is dependent on two CHR elements and one CDE site in the MKI67 promoter.
Sigrid Uxa +5 more
openaire +2 more sources
Comparison of Ki-67 equivalent antibodies [PDF]
To compare commercially available Ki-67 equivalent antibodies with regard to qualitative and quantitative immunohistochemical staining characteristics.The following antibodies were used: monoclonal MIB-1 (Immunotech), monoclonal MM1 (Novocastra), polyclonal NCL-Ki-67p (Novocastra), and polyclonal Rah Ki-67 (Dako).
C F, Lindboe, S H, Torp
openaire +2 more sources
As neoplasias astrocitárias correspondem a 60% dos tumores do sistema nervoso central, sendo o estudo da biologia molecular um importante passo para a compreensão da gênese e comportamento biológico destas doenças.
Gustavo Rassier Isolan +7 more
doaj +1 more source
Ki‐67 labeling in postmitotic cells defines different Ki‐67 pathways within the 2c compartment [PDF]
AbstractSimultaneous quantification of DNA and Ki‐67 proliferation‐associated antigen was performed using fluorescence image cytometry. In the MCF‐7 cell line, the Ki‐67 antigen content increases during the cell cycle, and its intranuclear distribution pattern varies.
S, du Manoir +4 more
openaire +2 more sources
Hubungan Ekspresi Ki-67 dengan Grading Histopatologi Liposarkoma
Liposarcoma, a malignant tumor of mesenchymal origin, was one of the most common sarcomas of adults and occurs primarily in the fifth through seventh decades of life. The occurrence in children was rare.
Afiati, Bethy S. Hernowo
doaj +1 more source
EXPRESSION OF OCT-4, P53, P16 AND KI-67, WITH HPV ASSOCIATED PRECANCER AND CANCER OF THE CERVIX
The pathology of cervical HPV infection is detected by three types of epithelial-mesenchymal spheroidal structures: reparative, neoplastic and cancerous involved in reparation processes and in tumor growth.
E A Kogan +3 more
doaj +1 more source
Background Ki-67 standard reference card (SRC) and artificial intelligence (AI) software were used to evaluate breast cancer Ki-67LI. We established training and validation sets and studied the repeatability inter-observers.
Lina Li +4 more
doaj +1 more source
The effect of metformin on biomarkers associated with breast cancer outcomes: a systematic review, meta-analysis, and dose–response of randomized clinical trials [PDF]
Purpose: Breast cancer is a leading cause of cancer mortality in developed countries. We performed a meta-analysis of randomized clinical trials to investigate the effect of metformin on biomarkers associated with breast cancer outcomes and to explore ...
Chhabra, M. +9 more
core +2 more sources
Leiomyoma of the uterus is a benign hormone-dependent tumors in women.The incidence of LM among gynecological diseases is 25 to 50%, according to different authors. In reproductive-aged women its frequency is about 30%.
E A Kogan +7 more
doaj +1 more source

