Results 231 to 240 of about 239,474 (338)

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

Potential of Corncob Extract on the Expression of Ki-67 and Caspase3 in Breast Cancer. [PDF]

Asian Pac J Cancer Prev
Fahria F, Budhy TI, Nugraha J, Suprabawati DGA, Plumeriastuti H, Pallupi R.   +5 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Relationship between Ki-67 and P53 immunohistochemical expression and osteosarcoma chemotherapy sensitivity and long-term prognosis. [PDF]

Am J Transl Res
Gu Z, Zhang S, Li G, Hu X, Xu N, Wang Y, Ruan J, Ma W, Chen H.   +8 more
europepmc   +1 more source

A Novel Nucleolar Protein, NIFK, Interacts with the Forkhead Associated Domain of Ki-67 Antigen in Mitosis

, 2001
Masatoshi Takagi, Mari Sueishi, Takuya Saiwaki, Ai Kametaka, Yoshihiro Yoneda   +4 more
openalex   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

Characterization of CD44+ALDH1+Ki-67– Cells in Non-malignant and Neoplastic Lesions of the Breast [PDF]

, 2016
Arnaud Da Cruz Paula, Oriana Marques, Rita Sampaio, Ana Margarida Rosa, José Palla Garcia, Alexandra Rêma, Maria De Fátima Faria, Paula Silva, José R. Vizcaíno, Carlos Lopes   +9 more
openalex   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

The impact of stratified management of Ki-67 on the prognosis of small-cell lung cancer. [PDF]

BMC Cancer
Zhang X, He M, Zheng G, Bai J.
europepmc   +1 more source

Inmuno directa Ki-67 (AF488) v1

Complete protocol for 3D bioprinted tissue engineered samples from Álvarez-Trujillo Lab using SC23900 Ki-67 conjugate antibody with AF488. Samples processed as this are to be seen on a fluorescent microscope. Proliferation proteins in cells alight green. Direct immuno fluorescent assay Ki-67 (AF488)
openaire   +1 more source