Results 281 to 290 of about 239,474 (338)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

open access: yesAdvanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi   +10 more
wiley   +1 more source

Association Between the Ki-67 Index, Tumor Size and Postoperative Structural Persistence in Non-functioning Pituitary Neuroendocrine Tumors: A Single-Center Experience. [PDF]

open access: yesCureus
Jimenez-Canizales CE   +6 more
europepmc   +1 more source

Efficacy Analysis of the Clinical, DL_RadScore, Radiomics, and Combined Models in Diagnosing Double-Positive Ki-67 and MVI in HCC.

open access: green
Hongmei Yu (584700)   +6 more
openalex   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

open access: yesAdvanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao   +8 more
wiley   +1 more source

Ki-67-Playing a key role in breast cancer but difficult to apply precisely in the real world. [PDF]

open access: yesBMC Cancer
Wang C   +9 more
europepmc   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Study of biomarkers p53, Ki-67, Bcl-2, and VEGF in pterygium

open access: diamond
Shilpa Ghosh   +4 more
openalex   +1 more source

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