Results 121 to 130 of about 146,439 (308)

A heterogeneously stained case of Ki67.

, 2015
Ki67 LI was high in upper areas and low in lower areas.
Baohua Yu (733656), Fei Yang (46361), Ruohong Shui (733655), Wentao Yang (205781), Rui Bi (196341)   +4 more
core   +1 more source

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

Advanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li, Anguo Zhao, Qi Zhuang, Lei Peng, Rui Liang, Jiadong Zhao, Yang Liu, Dashi Deng, Peng Yu, Xiqi Peng, Shaohua Zhang, Song Wu   +11 more
wiley   +1 more source

Ki67 protein was located at nucleus of the breast cancers.

, 2013
A(2+) and B(2+), Ki67 protein distributed as diffuse type; C(2+) and D(2+), Ki67 protein distributed as borderline type; E(2+), Ki67 protein expressed in the lymph node metastasis; F, negative control.
Zhongyu Wang (171066), Peng Gong (69507), Yingxin Wang (285577), Gavin Liu (285580), Jing Zhang (23775)   +4 more
core   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

MZF1 Inhibits TGFβ‐1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer

Advanced Science, EarlyView.
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng, Mengxi Huang, Yiting Wang, Hongyu Wang, Haimei Feng, Xiaoming Bai, Jie Chen, Ke Xu, Xiaoyuan Chu, Zengjie Lei   +9 more
wiley   +1 more source

Effects of andrographolide on p53 and Ki67 expression in an experimental mouse model of endometriosis

Journal of Advanced Biotechnology and Experimental Therapeutics
Endometriosis is a long-term condition that causes inflammation and leads to the growth of abnormal tissue outside the uterus. This tissue can cause significant problems, including pain and infertility.
Indra Adi Susianto, Inu Mulyantoro, Aprilia Karen Mandagie, Alberta Widya Kristanti, Edward Indra Hartono, Fransisca Pramesshinta Hardimarta   +5 more
doaj   +1 more source

Ki67 expression in different cell cycle phases.

, 2015
Cells express Ki67 during G1, S, G2, and mitotic phases but not during G0. Ki67 levels are low in the G1 and S phases and rise to peak level in mitotic phase; the depth of red color represents Ki67 expression levels, the deeper the higher.
Jia Mei Chen (719800), Lin Wei Wang (719798), Dai-Wen Pang (49408), Ai Ping Qu (719799), Juan Liu (6492), Chuang Chen (496438), Qing Ming Xiang (719801), Yan Li (23143), Jing Ping Yuan (719797), Sheng-Rong Sun (496439)   +9 more
core   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67

Frontiers in Oncology
ObjectiveTo investigate the optimal cut-off value of immunohistochemical marker Ki67 as a prognostic factor to predict the recurrence of non-muscle invasive bladder urothelial carcinoma (NMIBUC).MethodsA total of 331 patients diagnosed with NMIBUC who ...
Rende Peng, Yaoyu Zhang, Mingzhu Jia, Xinping Yi, Xiaoyao Yi, Shadan Li, Jiangchuan Pi, Wenjun Meng   +7 more
doaj   +1 more source

Ki67 and p53 in rectal cancer patients after neoadjuvant treatment

, 2007
Introdução: O câncer colorretal é uma das neoplasias mais freqüentes e a recorrência local é um grande desafio, pois provoca sintomas que incomodam o paciente e são de difícil resolução médica. .
Santos, Nara Rosana Andrade [UNIFESP]
core