Results 111 to 120 of about 146,439 (308)

CORRELATION OF Ki67 EXPRESSION TO DEGREE OF DYSPLASIA IN LINGUAL EPITHELIAL DYSPLASIA IN Rattus norvegicus EXPOSURED BY CIGARETTE SMOKE (Hubungan Ekspresi Ki67 Terhadap Derajat Displasia Pada Epitel Mukosa Lidah Rattus norvegicus yang Dipapar Asap Rokok)

ODONTO: Dental Journal, 2019
Background: Dysplasia is malignant transformation of stratified squamous epithelium characterized by cellular atypia and loss of stratification and maturation. It can caused by cigarette smoke.
Rina Kartika Sari, Hening Tuti Hendarti, Bagus Soebadi, Priyo Hadi, Desiana Radithia, Adiastuti Endah P   +5 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Inverse correlation between Ki67 expression as a continuous variable and outcomes in luminal HER2-negative breast cancer

Fujita Medical Journal, 2019
Objectives: Few studies to date have investigated the prognostic significance of Ki67 expression as a continuous variable in breast cancer. This study aimed to evaluate the impact of Ki67 expression as a dichotomous or continuous variable on outcomes in ...
Kaori Ushimado, Naomi Kobayashi, Masahiro Hikichi, Tetsuya Tsukamoto, Makoto Urano, Toshiaki Utsumi   +5 more
doaj   +1 more source

EdU captures all proliferative events detected by Ki67.

, 2016
(a-b) Immunostaining by Lab #2 for insulin (yellow), Ki67 (green), EdU (red), and DAPI (blue). Scale bar: 100 μm. Insets demonstrate (a) Ki67+ EdU+ co-positive cells and (b) a rare Ki67+ EdU- cell. (c-d) Quantification of Ki67+ cells co-expressing EdU in
Peng Yi (1482598), Erica P. Cai (3154248), Claire W. Bonnyman (3154245), Carol J. Lam (752024), Douglas A. Melton (529913), Jacqueline S. Rios (3154251), Julia Chavez (3154242), Jake A. Kushner (752029), Aaron R. Cox (752025), Ornella Barrandon (269997)   +9 more
core   +1 more source

The CXCL5/CXCR2 Axis Attenuates Ferroptosis in Intrahepatic Cholangiocarcinoma Through the Positive Feedback Loop Between PTGS2 Transcriptional Activation and Neutrophil Recruitment

Advanced Science, EarlyView.
The CXCL5/CXCR2 axis directly inhibits ferroptosis in ICC cells by activating the NF‐κB/PTGS2 pathway. Meanwhile, the CXCL5/CXCR2 axis recruits N2 TANs, and the activated PTGS2 promotes the secretion of TNF‐α from the recruited N2 TANs via the CCL2/CCL7/CCR2 pathway, thereby activating the NF‐κB/PTGS2 axis and forming a positive feedback loop, which ...
Chanqi Ye, Kefeng Lin, Shuyao Yang, Yan Zhang, Wenli Gao, Jiaqi Chen, Ying Dong, Rui Bai, Yang Tian, Minghao Wang, Zhijun Yuan, Yuxiao Ma, Yuqin He, Ruyin Chen, Wenguang Fu, Qi Jiang, Qiong Li, Jian Ruan   +17 more
wiley   +1 more source

Correlation between Ki67 and Breast Cancer Prognosis

Oncology, 2013
<b><i>Background:</i></b> Ki67 is an immunohistochemical proliferation marker in many types of cancer and has been widely studied among breast cancer patients mostly through retrospective studies. <b><i>Methods:</i></b> The MEDLINE/PubMed database was searched for publications with the medical subject ...
Kontzoglou, K., Palla, V., Karaolanis, G., Karaiskos, I., Alexiou, I., Pateras, I., Konstantoudakis, K., Stamatakos, M.   +7 more
openaire   +3 more sources

Evaluation of Telomerase (hTert), Ki67 and p16ink4a expressions in low and high-grade cervical intraepithelial lesions

, 2017
Objective : to study the association between the histological grading of cervical intraepithelial neoplasia (CIN I, CIN II and CIN III) and the immunohistochemical expression for p16ink4a, hTert and Ki67, as well as to evaluate the relationship of these
VINICIUS DUVAL DA-SILVA (5670005), MANOEL AFONSO GUIMARÃES GONÇALVES (5670002), ANA PAULA SZEZEPANIAK GOULART (5669999)   +2 more
core   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

A homogenously stained case of Ki67.

, 2015
High Ki67 LI was diffuse and homogenous across the slide.
Baohua Yu (733656), Fei Yang (46361), Ruohong Shui (733655), Wentao Yang (205781), Rui Bi (196341)   +4 more
core   +1 more source

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

Advanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu, Jingzhe Wang, Xu Chen, Yuntong Yang, Ping Wei, Han Xie, Honghao Wang, Chunyu Zhang, Siyi Xu, Qi Wang, Chunlong Zhong, Jing Zhang   +11 more
wiley   +1 more source