Results 91 to 100 of about 146,439 (308)
, 2018 Liang Zhao,1 Haojun Chen,2 Bin Hu,3 Huan Zhang,1 Qin Lin1 1Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China; 2Department of ...
Lin Q, Zhao L, Zhang H, Chen H, Hu B
core
Factors influencing Ki67 calculation in neuroendocrine neoplasia
, 2017 Aim: We compared different methodologies to evaluate Ki67 in neuroendocrine neoplasia (NEN). Patients & methods: ki67 was evaluated using three methods in 70 NEN cases: manual-count, eyeballed estimate made by three pathologists and ImmunoRatio ...
Miluska Castillo +10 more
core +1 more source
Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
, 2013 P1, Ki67+ group compared to Ki67− group; P2, Diffuse type compared to Ki67− group; P3, borderline type compared to diffuse type.
Zhongyu Wang (171066) +4 more
core +1 more source
Advanced Science, EarlyView.HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun +12 more
wiley +1 more source
Advanced Science, EarlyView.LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao +13 more
wiley +1 more source
The prognostic value of Ki67 in systemically untreated patients with node-negative breast cancer
, 2014 Aim To evaluate the utility of Ki67 as a prognostic marker in a series of patients with node-negative breast cancer untreated with adjuvant systemic therapy.
Bilinski, Kellie (R18510) +8 more
core +1 more source
Advanced Science, EarlyView.IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu +10 more
wiley +1 more source
Proliferating trichilemmal cyst: The value of ki67 immunostaining
International Journal of Trichology, 2013 A proliferating trichilemmal cyst (PTC) is an uncommon, rapidly-reproducing cutaneous epithelial cyst, differentiating from the isthmic portion of the outer hair root sheath. It is usually described as a benign tumor, but malignant transformation has been reported and is then denominated as a malignant proliferating trichilemmal tumor.
Rangel-Gamboa, Lucia +3 more
openaire +3 more sources
Digital quantification of Ki67 and PRAME in challenging melanocytic lesions - A novel diagnostic tool [PDF]
The interpretation of immunohistochemical markers in melanocytic lesions possesses difficulties due to expression in non-melanocytic cells and the time-consuming, non-reproducible nature of manual assessment.
Steiniche, Torben +6 more
core +1 more source