Results 81 to 90 of about 146,439 (308)

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Expression of Ki67 in Precancerous Squamous Cell Skin Lesion of Mice Induced by DMBA

Indonesian Journal of Cancer, 2019
Background: Squamous cell carcinoma (SCC) is an invasive skin cancer that is found in the human skin. SCC growth from the precancerous lesion is known as a wart or papilloma. Ki67 is a protein expressed by cells during proliferation. Cells with higher
Siti Nurkasanah, Aida S D Hoemardani, Evlina Suzanna Sinuraya   +2 more
doaj   +1 more source

Quantum dot-based immunofluorescent imaging of Ki67 and identification of prognostic value in HER2-positive (non-luminal) breast cancer

, 2014
Jin-Zhong Sun,1,* Chuang Chen,1,* Guan Jiang,2 Wei-Qun Tian,3 Yan Li,4 Sheng-Rong Sun1 1Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China; 2Department of Dermatology, Renmin ...
Sun JZ, Li Y, Jiang G, Sun SR, Tian WQ, Chen C   +5 more
core  

Airway epithelial proliferation (Ki67) and pERK1/2.

, 2018
(A-D Ki67): (A) Percent of airway epithelial cells that are Ki67 positive. (B) Saline CPAP 6 hour animals (SC6) have minimal staining. (C) Saline Ventilation 6 hour (SV6) animals have increased lung congestion without increased Ki67 signal in the airways.
T. Brett Kothe (5513738), Masatoshi Saito (498633), Emily Royse (3146850), Noah H. Hillman (556724), Matthew W. Kemp (320771), Gabrielle C. Musk (815006), Alan H. Jobe (320777), Haruo Usuda (815002)   +7 more
core   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Ki67 labeling in CNS tumours

Indian Journal of Pathology and Oncology, 2019
A study of Ki67 Labeling Index (LI) by immunohistochemistry was carried out in 47 CNS neoplasms. Astrocytic and oligodendroglial tumours were the most common group with glioblastoma, NOS and diffuse astrocytoma, NOS Grade II predominating. Ki67 LI of diffuse astrocytomas varied from 0.72 to 13.9% with a mean of 4.36%.
Manjiri Karandikar, Narayanan Subramanian Mani, Uttara Mani   +2 more
openaire   +1 more source

Establishment and validation of glioma patient-derived organoid models

Glioma
Background and Aim: Glioma is one of the most prevalent and refractory brain cancers with a high recurrence rate. Current limitations of experimental in vitro models include their inability to remodel the heterogeneity of the parental tumors and their ...
Anqi Wang, Xiangtong Xie, Lu Hao, Xuetao Li, Yulun Huang, Zhimin Wang   +5 more
doaj   +1 more source

Ki67 protein and gene expression analysis.

, 2014
(A) MKI67 mRNA expression levels and relationship to Ki67 protein staining levels as determined by IHC. (B) Differentially expressed genes associated with Ki67 high or low protein staining levels (p-values indicated).
Rachel N. Tam (521257), Rupal Desai (111308), Timothy R. Wilson (383252), Jill M. Spoerke (242323), Erica B. Schleifman (521252), Yuanyuan Xiao (10731), Hartmut Koeppen (40078), Carol O’Brien (521255), Ling Fu (162265), Ilma Abbas (521254), Rajesh Patel (52036), Mark R. Lackner (242333), Teiko Sumiyoshi (521256), Garret M. Hampton (383253), Cheryl Wong (521253), Rajiv Raja (111316)   +15 more
core   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Evaluation of Telomerase (hTert), Ki67 and p16ink4a expressions in low and high-grade cervical intraepithelial lesions

, 2017
Objective : to study the association between the histological grading of cervical intraepithelial neoplasia (CIN I, CIN II and CIN III) and the immunohistochemical expression for p16ink4a, hTert and Ki67, as well as to evaluate the relationship of these
ANA PAULA SZEZEPANIAK GOULART, VINICIUS DUVAL DA-SILVA, MANOEL AFONSO GUIMARÃES GONÇALVES   +2 more
core   +2 more sources