Results 71 to 80 of about 146,439 (308)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Prognostic Significance of Bcl-2 and p53 Protein Expressions and Ki67 Proliferative Index in Diffuse Large B-cell Lymphoma

Turkish Journal of Hematology, 2013
Objective: Diffuse large B-cell lymphoma (DLBCL) is a high-grade neoplasm that has heterogeneous properties in clinical, morphological, and immunophenotypic aspects.
Betül Bolat Küçükzeybek, Sadi Bener, Aylin Orgen Çallı, Tuğba Doğruluk Paksoy, Bahriye Payzin   +4 more
doaj   +1 more source

Ki67 staining in HUVECs.

, 2014
(A) Ki67 staining in HUVECs that had been treated with PBS (control) or irisin (20 nM) for 24 h. Images were taken with a confocal microscope. (B) Proliferation was assessed by the ratio of the average number of Ki67-positive cells to total cells in 10 ...
Xing Li Wang (136128), Shiwu Li (460656), Lijun Yang (356935), Taixing Cui (136134), Haibo Song (648222), Yuan Zhang (41832), Zhongde Wang (476556), Fang Wang (105926), Dongqi Tang (136130), Fei Wu (117860), Miao Jiang (442328), Mingxiang Zhang (126631), Yuzhu Zhang (648223)   +12 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Peculiarities of proliferative activity of non-small cell lung cancer in case of tumor spread through air spaces

Бюллетень сибирской медицины
Aim. To study the proliferative activity of non-small cell lung cancer with tumor spread through air spaces.Materials and methods. The study included 88 patients with stage IA-IIIA non-small cell lung cancer.
M. V. Zavyalova, A. A. Durova, A. V. Zavyalov, S. V. Miller, N. V. Krakhmal, D. S. Pismenny, N. S. Telegina, S. V. Vtorushin, V. M. Perelmuter   +8 more
doaj   +1 more source

Clinical and morphological characteristics of wound healing in diabetic foot syndrome

Сахарный диабет, 2017
Aim. To assess the clinical and morphological characteristics of neuropathic diabetic foot ulcers (DFUn) Materials and Methods. Forty-three specimens of DFUn were analysed.
Elena Yur'evna Komelyagina, Eugenia Alexandrovna Kogan, Mikhail Borisovich Antsiferov   +2 more
doaj   +1 more source

Proliferation scores in canine anal sac adenocarcinomas: Ki67 global score is superior to Ki67 hotspot indices and mitotic count for prognosis

Canine anal sac adenocarcinoma (ASAC) is an aggressive malignancy with high metastatic potential. Histologic and proliferation parameters such as mitotic count and Ki67 scores have limited prognostic value according to the published literature.
Avallone, Giancarlo, Brunetti, Barbara, Martinoli, Ginevra, Bacci, Barbara, Morisi, Ambra, Bacon, Nicholas J.   +5 more
core   +1 more source

An Activity‐Reinforced P‐Modified Single‐Atom Cu Nanozyme Potentiates IDO Blockade‐Induced Tumor Radiotherapy

Advanced Science, EarlyView.
A phosphorus‐modified single‐atom copper nanozyme delivering the IDO1 inhibitor 1‐methyl‐tryptophan enhances breast cancer radioimmunotherapy by simultaneously relieving hypoxia and inducing immunogenic cell death through dual enzyme activities while blocking tryptophan metabolism to suppress regulatory T cell function.
Wei Zhao, Songliu Hu, Zhanggui Wang, Liqun Wang, Liming Zhang, Qi Li, Hua Tang, Yang Zhong, Zhongxian Zhang, Kelong Fan, Shipeng Ning, Xiyun Yan   +11 more
wiley   +1 more source

Analysis of Baseline Serum Lipid Profile for Predicting Clinical Outcomes of Patients with Extensive-Stage Small Cell Lung Cancer

Cancer Management and Research, 2023
Mingshuang Wu,1 Yi He,1 Chenxi Pan2 1Department of Urology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 2Department of Breast Surgery, The Second Affiliated Hospital of Dalian Medical ...
Wu M, He Y, Pan C
doaj  

LARGE UTERINE LEIOMYOMAS: PATHOGENETIC MECHANISMS OF GROWTH

Клиническая практика, 2016
The pathogenesis of uterine fibroids remains controversial and raises many questions. The causes and mechanism of development of large leiomyoma are unknown.
E A Kogan, S I Askolskaya, Yu V Popov, M A Solomakhina, N M Fayzullina   +4 more
doaj   +1 more source