Results 61 to 70 of about 146,439 (308)

Evaluation of P57, P53 and Ki67 Expression in Meningiomas

open access: yesJournal of Korean Neurosurgical Society, 2022
Objective : We conducted this study with the aim of predicting the biological behavior of meningiomas, and determining the benefits of associating histological subtype and grade with the expression of proliferative markers and tumor suppressor proteins.Methods : The study included 29 patients with primary intracranial and intraspinal meningioma ...
İlknur Küçükosmanoğlu   +3 more
openaire   +2 more sources

A heterogeneously stained case of Ki67.

open access: yes, 2016
With a high Ki67 LI on the left and a low Ki67 LI on the right.
Baohua Yu (733656)   +5 more
core   +1 more source

Digital Image Analysis of the Proliferation Markers Ki67 and Phosphohistone H3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Accuracy of Grading Compared With Routine Manual Hot Spot Evaluation of the Ki67 Index [PDF]

open access: yes, 2021
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare epithelial neoplasms. Grading is based on mitotic activity or the percentage of Ki67-positive cells in a hot spot.
Søreide, Kjetil   +11 more
core   +1 more source

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong   +20 more
wiley   +1 more source

Correlation of Securin and Ki67 in Invasive Breast Carcinoma

open access: yesThe FASEB Journal, 2018
Introduction Apart from skin malignancies, breast cancer ranks the second most common malignancy in females worldwide. The increasing trends of breast cancer have led to plethora of studies in attempt to identify biological markers that may identify patients who may develop local recurrence or metastasis.
Talaat, IM   +4 more
openaire   +4 more sources

Various patterns of Ki67 expression in BC.

open access: yes, 2015
Ki67 grade I and Ki67/CK grade II in BC tissues (A, 200 ×); Ki67 grade II and Ki67/CK grade I in BC tissues (B, 200 ×); Ki67 is mainly expressed in cancer cell nucleus (C, yellow arrows, 200 ×), with few exceptions in stroma (C, red arrows), not in blood
Jia Mei Chen (719800)   +9 more
core   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang   +8 more
wiley   +1 more source

The Ki67 dilemma: investigating prognostic cut-offs and reproducibility for automated Ki67 scoring in breast cancer

open access: yesBreast Cancer Research and Treatment
Abstract Purpose Quantification of Ki67 in breast cancer is a well-established prognostic and predictive marker, but inter-laboratory variability has hampered its clinical usefulness. This study compares the prognostic value and reproducibility of Ki67 scoring using four ...
Emma Rewcastle   +5 more
openaire   +2 more sources

Inflammatory myofibroblastic tumor manifesting as recurrent generalized gingival enlargement: Report of a rare case

open access: yesIndian Journal of Pathology and Microbiology, 2020
Oral inflammatory myofibroblastic tumor (IMT) is extremely rare and its manifestation as generalized gingival enlargement (GGE) has never been reported.
Vikender S Yadav   +3 more
doaj   +1 more source

Eradication of Infection Restores ki67, p53, and Cyclin D1 Immunoreactivity in the Human Gastric Epithelium

open access: yes, 2016
Introduction We evaluated the effect of Helicobacter pylori (HP) eradication on p53, cyclin D1 expression, and cell proliferation in gastric mucosa. Materials and Methods We assessed p53, cyclin D1, and ki67 immunoexpression in gastric mucosa from 31 HP ...
Paraskevas Gkolfakis   +9 more
core   +1 more source

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