Results 61 to 70 of about 177,505 (309)
Brain Sciences, 2020 Glioblastoma is a solid, infiltrating, and the most frequent highly malignant primary brain tumor. Our aim was to find the correlation between sex, age, preoperative Karnofsky performance status (KPS), presenting with seizures, and extent of resection ...
Maurizio Salvati +12 more
doaj +1 more source
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke. [PDF]
, 2019 Stroke is the leading cause of adult disability. Neurogenesis after stroke is associated with repair; however, the mechanisms regulating poststroke neurogenesis and its functional effect remain unclear. Here, we investigate multiple mechanistic routes of
Carmichael, S Thomas +8 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Risk Management and Healthcare Policy, 2020 Xin Jin, Xin Zhao, Xingsheng Liu, Ke Han, Gaojun Lu, Yi Zhang Thoracic Surgery Department, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Yi ZhangThoracic Surgery Department, Xuanwu Hospital, Capital
Jin X +5 more
doaj
ODONTO: Dental Journal, 2019 Background: Dysplasia is malignant transformation of stratified squamous epithelium characterized by cellular atypia and loss of stratification and maturation. It can caused by cigarette smoke.
Rina Kartika Sari +5 more
doaj +1 more source
Cell kinetic markers in cutaneous squamous and basal cell carcinoma of the head and neck
Brazilian Journal of Otorhinolaryngology, 2022 Introduction: Proliferation markers play a significant role in the biologic behavior of tumors. Geminin is a known inhibitor of the cell cycle and DNA replication and has not been previously reported in cutaneous basal and squamous cell carcinomas of the
Mojgan Alaeddini +1 more
doaj +1 more source
Modelling hippocampal neurogenesis across the lifespan in seven species
, 2011 The aim of this study was to estimate the number of new cells and neurons added to the dentate gyrus across the lifespan, and to compare the rate of age-associated decline in neurogenesis across species.
Lazic, Stanley E.
core +1 more source
Evaluation of P57, P53 and Ki67 Expression in Meningiomas
Journal of Korean Neurosurgical Society, 2022 Objective : We conducted this study with the aim of predicting the biological behavior of meningiomas, and determining the benefits of associating histological subtype and grade with the expression of proliferative markers and tumor suppressor proteins.Methods : The study included 29 patients with primary intracranial and intraspinal meningioma ...
İlknur Küçükosmanoğlu +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Fujita Medical Journal, 2019 Objectives: Few studies to date have investigated the prognostic significance of Ki67 expression as a continuous variable in breast cancer. This study aimed to evaluate the impact of Ki67 expression as a dichotomous or continuous variable on outcomes in ...
Kaori Ushimado +5 more
doaj +1 more source