Results 41 to 50 of about 202,716 (285)

Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer [PDF]

, 2015
Introduction Aromatase inhibitors (AIs) are a vital component of estrogen receptor positive (ER+) breast cancer treatment. De novo and acquired resistance, however, is common.
A Mackay, AK Dunbier, AK Dunbier, Alan Mackay, Alexey Larionov, Anita K Dunbier, Aradhana Rani, Ash Nerurkar, B Weigelt, BP Coe, C Curtis, C Kent, D Generali, DG Albertson, DS Tan, Elena López-Knowles, F Kreisel, Helen Anderson, HW Cheung, IE Smith, IE Smith, J Hicks, J Michael Dixon, Jorge S Reis-Filho, JS Foster, K Lundgren, L Osterberg, LA Martin, LA Martin, LA Martin, Lesley-Ann Martin, LG Leon, Lorna Renshaw, M Dowsett, M Mello-Grand, M Scaltriti, Mitch Dowsett, MJ Ellis, MT Weigel, N Turner, P Darbre, P Lal, Paul M Wilkerson, Peter Osin, PM Wilkerson, PM Wilkerson, PT Simpson, R Beroukhim, R Duprez, R Katz-Brull, R Natrajan, R Natrajan, R Natrajan, Ricardo Ribas, T Miyake, T Troiani, TK Lam, William R Miller, WR Miller, WR Miller, WR Miller, WR Miller, X Huo, Y Zhao, Z Ghazoui, Zara Ghazoui   +65 more
core   +3 more sources

Neoadjuvant endocrine therapy for luminal breast cancer treatment: a first-choice alternative in times of crisis such as the COVID-19 pandemic [PDF]

, 2020
The epidemiological emergency caused by CoV-2 (COVID-19) has changed priorities in breast cancer management. In those places where the pandemic has had the greatest effect, it is of paramount importance for most patients to be at home, reducing or ...
Martí, Covadonga, Sánchez-Méndez, José I.   +1 more
core   +1 more source

p16/ki67 and E6/E7 mRNA accuracy and prognostic value in triaging HPV DNA-positive women.

Journal of the National Cancer Institute, 2020
BACKGROUND The study presents cross-sectional accuracy of E6/E7 mRNA detection and p16/ki67 dual staining, alone or in combination with cytology and HPV16/18 genotyping, as triage test in HPV DNA-positive women and their impact on CIN2+ overdiagnosis ...
P. Giorgi Rossi, F. Carozzi, G. Ronco, E. Allia, S. Bisanzi, Anna Gillio-Tos, L. Marco, Raffaella Rizzolo, D. Gustinucci, A. Del Mistro, H. Frayle, M. Confortini, A. Iossa, E. Cesarini, S. Bulletti, B. Passamonti, S. Gori, Laura Toniolo, A. Barca, Laura Bonvicini, P. Mancuso, F. Venturelli, M. Benevolo   +22 more
semanticscholar   +1 more source

MiR-205-5p inhibition by locked nucleic acids impairs metastatic potential of breast cancer cells [PDF]

, 2018
Mir-205 plays an important role in epithelial biogenesis and in mammary gland development but its role in cancer still remains controversial depending on the specific cellular context and target genes.
De Cola A., De Laurenzi V., Iezzi M., Lamolinara A., Lanuti P., Marchisio M., Rossi C., Todaro M.   +7 more
core   +1 more source

Cutoff of 25% for Ki67 expression is a good classification tool for prognosis in colorectal cancer in the AJCC-8 stratification

Oncology Report, 2020
Ki-67 expression has been widely used in clinical practice as an index to evaluate the proliferative activity of tumor cells. The cutoff for Ki67 expression in order to increase the prognostic value of Ki67 expression in colorectal cancer varies.
Guojun Tong, Guiyang Zhang, Jian Liu, Zhaozheng Zheng, Yan Chen, Pingping Niu, Xuting Xu   +6 more
semanticscholar   +1 more source

Ki67 Proliferation Index in Germinal and Non-Germinal Subtypes of Diffuse Large B-Cell Lymphoma

Cureus, 2021
Introduction Diffuse large B-cell lymphoma (DLBCL) is an aggressive B-cell lymphoma. The 2016 World Health Organization (WHO) update on hematopoietic tumors suggested that all DLBCL cases should be subtyped into germinal and non-germinal center ...
A. Hashmi, Syeda N Iftikhar, Gul Nargus, O. Ahmed, Ishaq A Asghar, Umme Aiman Shirazi, Anoshia Afzal, M. Irfan, J. Ali   +8 more
semanticscholar   +1 more source

Preserving dense features for Ki67 nuclei detection

Medical Imaging 2022: Digital and Computational Pathology, 2022
Published in SPIE Medical Imaging 04/2022: Digital and Computational Pathology; 120390Y.
Mirjahanmardi, Seyed Hossein, Dawe, Melanie, Fyles, Anthony, Shi, Wei, Liu, Fei-Fei, Done, Susan, Khademi, April   +6 more
openaire   +2 more sources

Targeting PKCθ promotes satellite cell self-renewal [PDF]

, 2020
Skeletal muscle regeneration following injury depends on the ability of satellite cells (SCs) to proliferate, self-renew, and eventually differentiate. The factors that regulate the process of self-renewal are poorly understood. In this study we examined
Benedetti, Anna, Bouché, Marina, Fiore, Piera Filomena, Lozanoska-Ochser, Biliana, Madaro, Luca   +4 more
core   +1 more source

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics [PDF]

, 2009
Prostate cancer cells with stem cell characteristics were identified in human prostate cancer cell lines by their ability to form from single cells self-renewing prostaspheres in non-adherent cultures.
A de la Taille, A Glinka, A van Bokhoven, AA George, AP Verhagen, AS Waller, AT Collins, AT Collins, AT Collins, B Hoang, B Mao, BA Reynolds, C Lo Celso, C Wissmann, CC Carson 3rd, CI Truica, CL Hall, CL Hall, D Beier, D Bonnet, D Masiello, D Mizrak, DA Lawson, David M Prowse, DK Singla, DL Hudson, DL Hudson, DP Petrylak, DR Chesire, EM Hurt, G Dontu, G Gu, G Shaw, G Shaw, GD Richardson, GJ van Leenders, GL Shaw, GN Thalmann, H Clevers, H Li, H Zhu, HF English, Isabelle Bisson, IV Litvinov, IV Litvinov, J Miki, JA Schalken, JE Visvader, JM Adams, KD Bunting, KG Leong, L Adam, L Patrawala, L Patrawala, L Patrawala, L Ricci-Vitiani, L Vezzoni, L Xin, L Xin, LE Pascal, LG Wang, M Al-Hajj, M Locke, M Verras, MJ Linja, MS Chen, MS Wicha, N Uchida, PN Kelly, RI Bhatt, S Signoretti, S Weiss, S Zhou, SI Hwang, SK Singh, SM Janes, SV Shmelkov, T Hara, T Nikolova, T Reya, WJ Huss, Y Katoh, Y Lu   +82 more
core   +1 more source

Digital Image Analysis of the Proliferation Markers Ki67 and Phosphohistone H3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Accuracy of Grading Compared With Routine Manual Hot Spot Evaluation of the Ki67 Index

Applied immunohistochemistry & molecular morphology (Print), 2021
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare epithelial neoplasms. Grading is based on mitotic activity or the percentage of Ki67-positive cells in a hot spot.
D. Lea, E. Gudlaugsson, Ivar Skaland, M. Lillesand, K. Søreide, J. Søreide   +5 more
semanticscholar   +1 more source