Results 41 to 50 of about 11,405,950 (406)
Progress of small ubiquitin-related modifiers in kidney diseases
Chinese Medical Journal, 2019 . Objective:. Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases.
Ou Li +6 more
doaj +1 more source
Diabetes and kidney cancer: A direct or indirect association? [PDF]
, 2010 A positive association between diabetes and kidney cancer has been reported in several investigations, but it is unclear whether diabetes or its complications account for this association.
Bahij S. Nuwayhid +4 more
core +2 more sources
Postbiotics and Kidney Disease
Toxins, 2022 Chronic kidney disease (CKD) is projected to become the fifth global cause of death by 2040 as a result of key shortcomings in the current methods available to diagnose and treat kidney diseases. In this regard, the novel holobiont concept, used to describe an individual host and its microbial community, may pave the way towards a better understanding ...
Chiara Favero +5 more
openaire +6 more sources
BMC Nephrology, 2020 Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee +4 more
doaj +1 more source
Transplantation in children [PDF]
, 1976 Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft.
Charles W. Putnam +15 more
core +1 more source
Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases
Cell Death Discovery, 2020 The transcription factor EB (TFEB) regulates the expression of target genes bearing the Coordinated Lysosomal Expression and Regulation (CLEAR) motif, thereby modulating autophagy and lysosomal biogenesis.
Wei-huang Zhang +4 more
semanticscholar +1 more source
Deprivation and kidney disease – a predictor of poor outcomes [PDF]
, 2019 There is a growing body of evidence for the role of deprivation in a broad spectrum of diseases including renal disease. Deprivation has been demonstrated to be associated with poorer outcomes across a range of renal diseases including acute kidney ...
Bell, Samira, Guthrie, Greg D.
core +2 more sources
Phytotherapy Research, 2020 Abelmoschus manihot, also called as “Huangkui” in Chinese, is an annual flowering herb plant in the family of Malvaceae. As a traditional Chinese medicine, the ethanol extract of the flower in Abelmoschus manihot is made as Huangkui capsule and has been ...
Nan Li +8 more
semanticscholar +1 more source
Targeting kidney mesangium by nanoparticles of defined size [PDF]
, 2011 Nanoparticles are being investigated for numerous medical applications and are showing potential as an emerging class of carriers for drug delivery. Investigations on how the physicochemical properties (e.g., size, surface charge, shape, and density of ...
C. H. J. Choi +19 more
core +2 more sources
The Many Faces of Matrix Metalloproteinase-7 in Kidney Diseases
Biomolecules, 2020 Matrix metalloproteinase-7 (MMP-7) is a secreted zinc-dependent endopeptidase that is implicated in regulating kidney homeostasis and diseases. MMP-7 is produced as an inactive zymogen, and proteolytic cleavage is required for its activation.
Zhao Liu, R. Tan, Youhua Liu
semanticscholar +1 more source