Results 11 to 20 of about 4,640,867 (405)

Matrix metalloproteinase-10 protects against acute kidney injury by augmenting epidermal growth factor receptor signaling

open access: yesCell Death and Disease, 2021
Matrix metalloproteinase-10 (MMP-10) is a zinc-dependent endopeptidase involved in regulating a wide range of biologic processes, such as apoptosis, cell proliferation, and tissue remodeling.
Chengxiao Hu   +9 more
doaj   +1 more source

The kidney failure risk equation predicts kidney failure: Validation in an Australian cohort

open access: yesNephrology, 2023
Predicting progression to kidney failure for patients with chronic kidney disease is essential for patient and clinicians' management decisions, patient prognosis, and service planning.
G. Irish   +5 more
semanticscholar   +1 more source

Smoking and Risk of Kidney Failure in the Singapore Chinese Health Study [PDF]

open access: yes, 2013
Background:The relationship between smoking and risk of kidney failure, especially in people of Chinese origin, is not clear. We analyzed data from the Singapore Chinese Health Study to investigate whether smoking increases the risk of kidney failure ...
AD Lopez   +32 more
core   +6 more sources

PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

open access: yesCell Death and Disease, 2021
Phosphatase and Tensin Homolog on chromosome Ten (PTEN) has emerged as a key protein that governs the response to kidney injury. Notably, renal adaptive repair is important for preventing acute kidney injury (AKI) to chronic kidney disease (CKD ...
Huizhen Wang   +6 more
doaj   +1 more source

Kidney failure in Samoa [PDF]

open access: yesThe Lancet Regional Health - Western Pacific, 2020
There is limited literature on kidney disease in the Pacific Region, despite it being recognised as a leading cause of death in some Pacific Island nations. Kidney replacement therapy is only available in a handful of Pacific Islands. This paper reports the epidemiology of haemodialysis patients in Samoa.Registry data from the National Kidney ...
Malama Tafuna'i   +7 more
openaire   +3 more sources

Classification of Uremic Toxins and Their Role in Kidney Failure.

open access: yesAmerican Society of Nephrology. Clinical Journal, 2021
Advances in our understanding of uremic retention solutes, as well as improvements in hemodialysis membranes and other techniques designed to remove uremic retention solutes, offer opportunities to readdress the definition and classification of uremic ...
M. Rosner   +15 more
semanticscholar   +1 more source

Joint effect of visit-to-visit variability in LDL-cholesterol, HDL-cholesterol and HbA1c on cardiovascular and total mortality in patients with diabetes

open access: yesDiabetology & Metabolic Syndrome, 2022
Background We aimed to investigate the joint effect of visit-to-visit variability (VVV) in low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides and glycosylated hemoglobin (HbA1c) on cardiovascular ...
Panpan He   +10 more
doaj   +1 more source

Salt-induced phosphoproteomic changes in the subfornical organ in rats with chronic kidney disease

open access: yesRenal Failure, 2023
Objectives Subfornical organ (SFO) is vital in chronic kidney disease (CKD) progression caused by high salt levels. The current study investigated the effects of high salt on phosphoproteomic changes in SFO in CKD rats.Methods 5/6 nephrectomized rats ...
Xin Wang   +5 more
doaj   +1 more source

Kidney Failure Prediction Models: A Comprehensive External Validation Study in Patients with Advanced CKD

open access: yesJournal of the American Society of Nephrology, 2021
Visual Abstract Significance Statement Most kidney failure prediction models have been developed and validated in cohorts of patients with a wide range of disease severity, without accounting for the competing risk of death.
Chava L. Ramspek   +13 more
semanticscholar   +1 more source

High-Salt Diet Accelerated the Decline of Residual Renal Function in Patients With Peritoneal Dialysis

open access: yesFrontiers in Medicine, 2021
Objective: This study aims to investigate the relationship between dietary salt intake and residual renal function in peritoneal dialysis (PD) patients.Methods: The daily salt intake of the patients was calculated based on a 3 day dietary record.
Nirong Gong   +12 more
doaj   +1 more source

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