Results 11 to 20 of about 1,022,396 (355)

Smoking and Risk of Kidney Failure in the Singapore Chinese Health Study [PDF]

open access: yes, 2013
Background:The relationship between smoking and risk of kidney failure, especially in people of Chinese origin, is not clear. We analyzed data from the Singapore Chinese Health Study to investigate whether smoking increases the risk of kidney failure ...
AD Lopez   +32 more
core   +10 more sources

Salt-induced phosphoproteomic changes in the subfornical organ in rats with chronic kidney disease

open access: yesRenal Failure, 2023
Objectives Subfornical organ (SFO) is vital in chronic kidney disease (CKD) progression caused by high salt levels. The current study investigated the effects of high salt on phosphoproteomic changes in SFO in CKD rats.Methods 5/6 nephrectomized rats ...
Xin Wang   +5 more
doaj   +1 more source

Joint effect of visit-to-visit variability in LDL-cholesterol, HDL-cholesterol and HbA1c on cardiovascular and total mortality in patients with diabetes

open access: yesDiabetology & Metabolic Syndrome, 2022
Background We aimed to investigate the joint effect of visit-to-visit variability (VVV) in low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides and glycosylated hemoglobin (HbA1c) on cardiovascular ...
Panpan He   +10 more
doaj   +1 more source

High-Salt Diet Accelerated the Decline of Residual Renal Function in Patients With Peritoneal Dialysis

open access: yesFrontiers in Medicine, 2021
Objective: This study aims to investigate the relationship between dietary salt intake and residual renal function in peritoneal dialysis (PD) patients.Methods: The daily salt intake of the patients was calculated based on a 3 day dietary record.
Nirong Gong   +12 more
doaj   +1 more source

A Klotho-derived peptide protects against kidney fibrosis by targeting TGF-β signaling

open access: yesNature Communications, 2022
Klotho is an anti-ageing protein whose expression is downregulated in chronic kidney disease, but the large size of the protein makes it challenging to deliver therapeutically.
Qian Yuan   +11 more
doaj   +1 more source

Klotho retards renal fibrosis through targeting mitochondrial dysfunction and cellular senescence in renal tubular cells

open access: yesPhysiological Reports, 2021
Chronic kidney disease (CKD) has a high prevalence worldwide and is an intricate issue to whole medical society. Renal fibrosis is the common pathological feature for various kinds of CKD.
Jinhua Miao   +7 more
doaj   +1 more source

The role of the kidney in heart failure [PDF]

open access: yesEuropean Heart Journal, 2012
Renal dysfunction is common in patients with heart failure and is associated with high morbidity and mortality. Cardiac and renal dysfunction may worsen each other through multiple mechanisms such as fluid overload and increased venous pressure, hypo-perfusion, neurohormonal and inflammatory activation, and concomitant treatment.
METRA, Marco   +4 more
openaire   +5 more sources

Development and Validation of a Risk Score for Prediction of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure: A Prospective Cohort Study in China

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundAlthough several risk factors for acute kidney injury (AKI) have been identified, early detection of AKI in acute decompensated heart failure patients remains a challenge. The aim of this study was to develop and validate a risk score for early
Li Zhi Zhou   +6 more
doaj   +1 more source

Positive association of triglyceride-glucose index with new-onset hypertension among adults: a national cohort study in China

open access: yesCardiovascular Diabetology, 2023
Background Previous studies showed that the triglyceride-glucose (TyG) index was a better predictor of adverse cardiovascular events than triglycerides or fasting blood glucose alone. However, few studies have focused on new-onset hypertension.
Qi Gao   +11 more
doaj   +1 more source

Dose of colistin. a work in progress? [PDF]

open access: yes, 2015
We thank Rashid and colleagues [1] and Honoré and colleagues [2] for their comments regarding our article on risk factors for acute kidney injury in pa- tients receiving colistin or other nephrotoxic antimi- crobials [3].
Antonelli, M.   +3 more
core   +1 more source

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