Results 11 to 20 of about 627,404 (266)

Development and Validation of a Risk Score for Prediction of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure: A Prospective Cohort Study in China

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundAlthough several risk factors for acute kidney injury (AKI) have been identified, early detection of AKI in acute decompensated heart failure patients remains a challenge. The aim of this study was to develop and validate a risk score for early
Li Zhi Zhou   +6 more
doaj   +1 more source

Klotho retards renal fibrosis through targeting mitochondrial dysfunction and cellular senescence in renal tubular cells

open access: yesPhysiological Reports, 2021
Chronic kidney disease (CKD) has a high prevalence worldwide and is an intricate issue to whole medical society. Renal fibrosis is the common pathological feature for various kinds of CKD.
Jinhua Miao   +7 more
doaj   +1 more source

dCubilin- or dAMN-mediated protein reabsorption in Drosophila nephrocytes modulates longevity

open access: yesDisease Models & Mechanisms, 2021
Aging is a multifaceted process regulated by multiple cellular pathways, including the proteostasis network. Pharmacological or genetic enhancement of the intracellular proteostasis network extends lifespan and prevents age-related diseases. However, how
Xiaoming Feng   +8 more
doaj   +1 more source

Kidney Transplant Failure [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2014
Kidney transplant failure is an important cause of dialysis initiation in the United States. In 2011, this group represented 4.7% of patients new to dialysis, a 30% increase in the number of patients initiating dialysis after transplant failure since 2000 ([1][1]).
openaire   +2 more sources

High-Salt Diet Accelerated the Decline of Residual Renal Function in Patients With Peritoneal Dialysis

open access: yesFrontiers in Medicine, 2021
Objective: This study aims to investigate the relationship between dietary salt intake and residual renal function in peritoneal dialysis (PD) patients.Methods: The daily salt intake of the patients was calculated based on a 3 day dietary record.
Nirong Gong   +12 more
doaj   +1 more source

Association of accelerometer-measured physical activity intensity, sedentary time, and exercise time with incident Parkinson’s disease

open access: yesnpj Digital Medicine, 2023
Evidence regarding the association between physical activity and Parkinson’s disease (PD) risk is generally limited due to the use of self-report questionnaires.
Mengyi Liu   +8 more
doaj   +1 more source

Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosisResearch in context

open access: yesEBioMedicine, 2022
Summary: Background: The role of the IL6 family members in organ fibrosis, including renal interstitial fibrosis (TIF), has been widely explored. However, few studies have ever simultaneously examined them in the same cohort of patients.
Shihui Xu   +14 more
doaj   +1 more source

Epidemiology of acute kidney injury in hospitalized pregnant women in China

open access: yesBMC Nephrology, 2019
Background Epidemiologic data of acute kidney injury (AKI) during pregnancy is lacking in China. This study aims to determine the effect of pregnancy on the risk of AKI among hospitalized women of childbearing age, and to describe the incidence, risk ...
Diankun Liu   +8 more
doaj   +1 more source

Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population

open access: yesAlzheimer’s Research & Therapy, 2023
Background The relationship of glucosamine use with incident dementia in the older population remains uncertain. We aimed to evaluate the longitudinal association between habitual glucosamine supplement and the risk of cause-specific dementia and examine
Chun Zhou   +8 more
doaj   +1 more source

Positive association of triglyceride-glucose index with new-onset hypertension among adults: a national cohort study in China

open access: yesCardiovascular Diabetology, 2023
Background Previous studies showed that the triglyceride-glucose (TyG) index was a better predictor of adverse cardiovascular events than triglycerides or fasting blood glucose alone. However, few studies have focused on new-onset hypertension.
Qi Gao   +11 more
doaj   +1 more source

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