Somatostatin-like immunoreactivity in the glomerulus of rat kidney
It has been shown that somatostatin inhibits the antidiuretic action of vasopressin in toad urinary bladder in vitro and in dogs and rats in vivo. The presence of somatostatin-like immunoreactivity (SLI) in the urinary bladder and kidney of the toad has suggested the possibility that somatostatin may act as a local paracrine hormone modulating the ...
Kiyoshi Kurokawa+3 more
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A neural network for glomerulus classification based on histological images of kidney biopsy [PDF]
Abstract Background Computer-aided diagnosis (CAD) systems based on medical images could support physicians in the decision-making process. During the last decades, researchers have proposed CAD systems in several medical domains achieving promising results.
Giacomo Donato Cascarano+13 more
openalex +6 more sources
Roles of PDGF receptor-beta in the structure and function of postnatal kidney glomerulus. [PDF]
Mesangial cell functions are critically regulated by platelet-derived growth factor receptor (PDGFR)-β signals. In contrast to the well-established role of PDGFR-β in the development of kidney glomerulus, its role in adult kidney glomerulus remains controversial.We deleted the PDGFR-β gene postnatally using the Cre-loxP system and analysed the long ...
T. Nakagawa+11 more
semanticscholar +4 more sources
Antioxidant‐oxidant balance in the glomerulus and proximal tubule of the rat kidney
Antioxidant and oxidative enzymes were examined in renal glomeruli and proximal tubules of healthy young rats (10‐12 weeks old), and results were related to the superoxide anion generation of these tissues. Activities of superoxide dismutases, catalase, and glutathione peroxidase were 3‐ to 6‐fold higher in proximal tubules than in glomeruli ...
Wilfried Gwinner+6 more
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Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing. [PDF]
Eng DG+7 more
europepmc +2 more sources
About three thousand resin vascular casts of human renal glomeruli were examined with a scanning electron microscope, and two extremely rare glomeruli with quadruple or quintuple efferent arterioles were found.
Takuro MURAKAMI+3 more
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Revealing VCAN as a Potential Common Diagnostic Biomarker of Renal Tubules and Glomerulus in Diabetic Kidney Disease Based on Machine Learning, Single-Cell Transcriptome Analysis and Mendelian Randomization [PDF]
Background Diabetic kidney disease (DKD) is recognized as a significant complication of diabetes mellitus and categorized into glomerular DKDs and tubular DKDs, each governed by distinct pathological mechanisms and biomarkers.
Li Jiang, Jie Jian, Xulin Sai, Xiai Wu
doaj +2 more sources
Towards Staining Independent Segmentation of Glomerulus from Histopathological Images of Kidney [PDF]
AbstractThis paper introduces a detection-based framework to segment glomeruli from digital scanning image of light microscopic slide of renal biopsy specimens. The proposed method aims to better use the precise localization ability of Faster R-CNN and powerful segmentation ability of U-Net.
Robin Liu, Lu Wang, Jim He, Wenfang Chen
openalex +3 more sources
Chronic Changes on Kidney Histology by a Multiclass Artificial Intelligence Model [PDF]
Introduction: Chronic changes in kidney histology are often approximated by using human vision but with limited accuracy. Methods: An interactive annotation tool trained an artificial intelligence (AI) model for segmenting structures on whole slide ...
Aleksandar Denic+12 more
doaj +2 more sources
Lower Podocyte Number per Glomerulus Associates With Progressive CKD. [PDF]
Denic A+12 more
europepmc +2 more sources